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ProteomicsPrediction of Mortality In Acute Respiratory Distress Syndrome
Acute Respiratory Distress Syndrome (ARDS) continues to have a high mortality. The objective of this study is to understand the differences in disease biology between survivors and non-survivors by characterizing BALF protein expression profiles in individual ARDS subjects.
ORGANISM(S): Homo sapiens (Human) 
2018-10-24 | PXD002672 | Pride
Bal Galaxyp Itraq Ards Biomarkers 2dlc-ms/ms 
TranscriptomicsmiRNA expression profiles in rat Acute Respiratory Distress Syndrome (ARDS)
Rat model of ARDS was induced by saline lavage and mechanical ventilation. miRNA from rat lungs were used for dual color DNA microarray hybridization with 3DNA 50 kit version 2. Two-condition experiment, CON vs. ARDS lung tissues. replicates: 6 control, 6 ARDS. One replicate per array.
ORGANISM(S): Rattus norvegicus 
2014-05-07 | E-GEOD-57223 | biostudies-arrayexpress
ProteomicsDifferentiating children with sepsis with and without acute respiratory distress syndrome using proteomics
Both sepsis and acute respiratory distress syndrome (ARDS) rely on imprecise clinical definitions leading to heterogeneity, which has contributed to negative trials. Because circulating protein/DNA complexes have been implicated in sepsis and ARDS, we aimed to develop a proteomic signature of DNA-bo...
ORGANISM(S): Homo sapiens (Human) 
2024-02-14 | PXD049377 | Pride
Nucleosome Dna-bound proteins Acute respiratory distress syndrome Sepsis Neutrophil 
TranscriptomicsSmall RNA-Seq of plasma-derived exosomes from Acute Respiratory Distress Syndrome patients and healthy subjects
Despite a significant progress in the treatment of Acute Respiratory Distress Syndrome (ARDS), our ability to identify early patients and predict outcome remains limited. In this study, we aimed to characterize small RNA content of plasma exosomes from ARDS patients in order to identify potential di...
ORGANISM(S): Homo sapiens 
2021-01-19 | E-MTAB-9991 | biostudies-arrayexpress
ProteomicsEvaluation And Characterization Of Acute Respiratory Distress Syndrome In Tree Shrews Through TMT Proteomic Method
Acute respiratory distress syndrome (ARDS), a common cause of acute fatal respiratory, is characterized by severe inflammatory lung injury as well as hallmarks of increased pulmonary vascular permeability, neutrophil infiltration, and macrophage accumulation. Tree shrew, a squirrel-like small animal...
ORGANISM(S): Tupaia chinensis 
2025-05-07 | PXD053328 | Pride
Acute respiratory distress syndrome  tree shrew  tmt proteomics  lungs  immunological responses 
TranscriptomicsGene expression profiles in rat Acute Respiratory Distress Syndrome (ARDS)
Rat model of ARDS was induced by saline lavage and mechanical ventilation. Total RNA from rat lungs were used for dual color DNA microarray hybridization with 3DNA 50 kit version 2. Two-condition experiment, CON vs. ARDS lung tissues. replicates: 5 control, 7 ARDS. One replicate per array.
ORGANISM(S): Rattus norvegicus 
2014-04-24 | E-GEOD-57011 | biostudies-arrayexpress
GenomicARDSnet and the iSPAAR Consortium: Genetic Studies

Acute Respiratory Distress Syndrome (ARDS)/ Acute Lung Injury (ALI) is a syndrome defined by the presence of acute hypoxemic respiratory failure, bilateral pulmonary infiltrates on chest radiograph, a known clinical risk factor (e.g. sepsis, pneumonia, trauma, gastric fluid aspiration, pancreatit...

phs000631 | dbGaP
TranscriptomicsTranscription profiling of human samples from patients with acute lung injury plus sepis vs sepsis controls to investigate interactions between genes involved in ALI/ARDS
The Acute Respiratory Distress Syndrome (ARDS)/Acute Lung Injury (ALI) was described 30 years ago, yet the interaction between specific sets of genes involved in this syndrome remains incompletely understood. Experiment Overall Design: 13 patients with ALI + sepsis and 21 patients with sepsis alone ...
ORGANISM(S): Homo sapiens 
2008-04-09 | E-GEOD-10474 | biostudies-arrayexpress
UnknownPedunculoside alleviates lipopolysaccharide-induced acute lung injury/acute respiratory distress syndrome by inhibiting NF-κB pathway.
Not available
S-EPMC12475281 | biostudies-literature
TranscriptomicsInflammasome-regulated cytokines are critical mediators of lung injury in humans.
A microarray analysis involving whole blood samples isolated from critically ill patients in the medical intensive care unit at Brigham and Women's Hospital. Four groups of intubated subjects undergoing mechanical ventilation were recruited for the study: those with sepsis alone (Sepsis), those wit...
ORGANISM(S): Homo sapiens 
2012-07-10 | E-GEOD-32707 | biostudies-arrayexpress
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