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OtherThe N-cadherin interactome in primary cardiomyocytes
Low levels of Cdh2-BioID2 were expressed in mouse primary neonatal cardiomyocytes using an adenoviral expression system. Infected cells were treated with biotin for 24 hours before lysis. Biotinylated proteins were precipitated from lysates using streptavidin beads. Protein samples were in-gel tryps...
ORGANISM(S): Mus Musculus 
2019-01-23 | MSV000083356 | MassIVE
TranscriptomicsTranscription profiling by array to assess epidemic methicillin-resistant Staphylococcus aureus 16 phenotypes induced by PBD conjugates
Objectives Pyrrolobenzodiazepine (PBD) dimers, tethered through inert propyldioxy or pentyldioxy linkers, possess potent bactericidal activity against a range of Gram-positive bacteria by virtue of their capacity to cross-link duplex DNA in sequence-selective fashion. Here we attempt to improve the ...
ORGANISM(S): Staphylococcus aureus 
2012-04-17 | E-BUGS-118 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of Arabidopsis wild type, cop1-4, hy5-1 mutant seedlings exposed to polychromatic radiation
Seven-day-old white-light-grown wild-type, cop1-4 or hy5-1 mutant Arabidopsis seedlings were exposed for fifteen minutes to polychromatic radiation with decreasing short-wave cut-off in the UV range (WG305 = +UV-B, WG327 = -UV-B) and samples were taken 1 h after the onset of irradiation.
ORGANISM(S): Arabidopsis thaliana 
2006-08-16 | E-MEXP-557 | biostudies-arrayexpress
TranscriptomicsA global network of transcription factors, involving E2A, EBF1 and FOXO1, that orchestrates the B cell fate
It is now established that the transcription factors E2A, EBF1 and FoxoM-BM- 1 play critical roles in B cell development. Here we show that E2A and EBF1 bound regulatory elements present in the Foxo1 locus. E2A and EBF1 as well as E2A and Foxo1, in turn, were wired together by a vast spectrum of cis...
ORGANISM(S): Mus musculus 
2010-06-12 | E-GEOD-21978 | biostudies-arrayexpress
OtherQuantitative proteomics of human NPC1I1061T (sic) mutant fibroblasts provides insights into the pathogenesis of Niemann-Pick Type C disease.
Data from ProteomeXchange, PXD ID: PXD001938. Experiment: WTvsI1061T_TMT_inj01, file: folder summary. Published as part of Mol Cell Proteomics. 2015 Apr 14 . From the Abstract: {{i}} In our study, an isobaric labeling based quantitative analysis of proteome of NPC1I1061T (sic) primary fibroblasts w...
ORGANISM(S): Homo_sapiens_viruses, Human 
GPM32320014822 | GPMDB
Resource Reanalysis 
Other,MultiomicsChevrette et al 2019 Insect-associated Streptomyces
Paper title: The antimicrobial potential of Streptomyces from insect microbiomes. Author list: Chevrette MG, Carlson CM, Ortega HE, Thomas C, Ananiev GE, Barns KJ, Book AJ, Cagnazzo J, Carlos C, Flanigan W, Grubbs KJ, Horn HA, Hoffmann FM, Klassen JL, Knack JJ, Lewin GR, McDonald BR, Muller L, Melo ...
ORGANISM(S): Pseudonocardia Kitasatospora Streptomyces Gordonia <actinomycete> 
2019-12-18 | MSV000084723 | MassIVE
TranscriptomicsCrosstalk between the effects of extracellular vesicles (Evs) and TNF on U937 human monocyte cell line
Under physiological conditions, extracellular vesicles (EVs) are present simultaneously in the extracellular compartment together with cytokines. Thus, we hypothesized that EVs in combination with cytokines induce different responses of monocyte cells compared to EVs or cytokines alone. Human monocy...
ORGANISM(S): Homo sapiens 
2013-06-19 | E-GEOD-47897 | biostudies-arrayexpress
GenomicsWTSI CGP Data access committee
Data Access Committee EGAC00001000000
EGAC00001000000 | EGA
GenomicsTRACERx Pilot Study Data Access Committee
Data Access Committee EGAC00001000198
EGAC00001000198 | EGA
Genomicsena-DATASET-CRUK-LRI-05-08-2014-14:10:54:243-46 - samples
Van Hippel-Lindau syndrome multi-region exome sequencing of two patients
EGAD00001000973 | EGA
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