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UnknownA double-blind, placebo-controlled, randomized trial of PXT3003 for the treatment of Charcot-Marie-Tooth type 1A.
Not available
S-EPMC8520617 | biostudies-literature
UnknownSqualenoyl siRNA PMP22 nanoparticles are effective in treating mouse models of Charcot-Marie-Tooth disease type 1 A.
Not available
S-EPMC7943818 | biostudies-literature
UnknownWhole genome sequencing reveals novel IGHMBP2 variant leading to unique cryptic splice-site and Charcot-Marie-Tooth phenotype with early onset symptoms.
Not available
S-EPMC6565564 | biostudies-literature
GenomicsModulation of enhancer looping and differential gene targeting by Epstein-Barr virus transcription factors directs epigenetic reprogramming
Epstein-Barr virus (EBV) epigenetically reprogrammes B-lymphocytes to drive immortalization and facilitate viral persistence. Host-cell transcription is perturbed principally through the actions of EBV EBNA 2, 3A, 3B and 3C, with cellular genes deregulated by specific combinations of these EBNAs thr...
ORGANISM(S): Homo sapiens 
2013-09-13 | E-GEOD-47629 | biostudies-arrayexpress
TranscriptomicsSRC1 gene regulation in endocrine resistant breast cancer cells
The development of breast cancer resistance to endocrine therapy results from an increase in cellular plasticity leading to the development of a steroid independent tumour. The p160 steroid coactivator protein SRC-1, through interactions with developmental proteins and other non-steroidal transcrip...
ORGANISM(S): Homo sapiens 
2012-01-11 | E-GEOD-28645 | biostudies-arrayexpress
ProteomicsCancer cell-derived ADAM15 dictates macrophage infiltration in colorectal tumors
Tumor progression and response to treatment is highly affected by interactions between cancer cells and the tumor microenvironment (TME). Many of the soluble factors and signaling receptors involved in this crosstalk are shed by a disintegrin and metalloproteinases (ADAMs). Upregulation of ADAM15 ha...
ORGANISM(S): Mus musculus (Mouse) 
2023-07-24 | PXD041164 | Pride
Lc-msms Cyr61 Mouse Tmt Ct26 Adam15 
UnknownDe novo transcriptome assembly, annotation and comparison of four ecological and evolutionary model salmonid fish species.
Not available
S-EPMC5759245 | biostudies-literature
UnknownTemporal stability of polymorphic Arctic charr parasite communities reflects sustained divergent trophic niches.
Not available
S-EPMC9636502 | biostudies-literature
UnknownUsing qPCR and microscopy to assess the impact of harvesting and weather conditions on the relationship between Alternaria alternata and Alternaria spp. spores in rural and urban atmospheres.
Not available
S-EPMC10267013 | biostudies-literature
TranscriptomicsMBains PAO1 cprR (CP28)
Micoarrays were used to obtain gene expression in mid-log phase PAO1::cprR(PA3077) with the treatment of 12ug/ml CP28 vs mid-log phase PAO1 with the treatment of 12ug/ml CP28
ORGANISM(S): Pseudomonas aeruginosa PAO1 
2012-12-05 | E-MTAB-1276 | biostudies-arrayexpress
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