Sort   by:  
 Page size 
ProteomicsInhibition of T cell activation and function by the CIN85 adaptor protein
CIN85 is ubiquitously expressed adaptor protein. In T cells, CIN85 is recruited to the TCR signaling complex and inhibit TCR signaling. To reveal the molecular function of CIN85-mediated inhibition, we performed Flag-CIN85 (CIN85dA) immuno-precipitation and identified the binding proteins. As a nega...
ORGANISM(S): Mus Musculus (mouse) 
2019-01-16 | PXD012369 | JPOST Repository
ProteomicsComprehensive Identification of Phosphorylation Sites on the Numb Endocytic Adaptor Protein
Numb is an endocytic adaptor protein that functions in the endocytosis and intracellular trafficking of membrane receptors and adhesion molecules. Numb localization and function have been shown to be regulated by phosphorylation through atypcial protein kinase C at several key sites. Here, we use ...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2016-10-04 | MSV000080218 | MassIVE
GenomicsThe essential clathrin adaptor protein complex-2 is tumor suppressive specifically in vivo
The essential clathrin adaptor protein complex-2 is tumor suppressive specifically in vivo
PRJNA975168 | ENA
TranscriptomicsTranscription profiling of Arabidopsis Mediator complex mutant pft1/med25 and wildtype infected with Fusarium oxysporum
The Mediator complex is an evolutionary conserved multiprotein complex that plays an essential role in initiating and regulating transcription. Its function is to act as a universal adaptor between RNA Polymerase II and DNA-bound transcription factors to translate regulatory information from activat...
ORGANISM(S): Arabidopsis thaliana 
2009-09-05 | E-GEOD-15236 | biostudies-arrayexpress
ProteomicsFAF2 enhances unfoldase activity of mammalian p97-UFD1-NPL4 complex enabling rational design of p97
To address how adaptor proteins impact human p97 activity, we here employ in vitro reconstitution and a focused biochemical screen to identify adaptors that enhance unfoldase activity of human p97 in the presence of UFD1-NPL4. Of the adaptors tested, Fas-associated factor 2 (FAF2/UBXD8), a UBX domai...
ORGANISM(S): Homo sapiens (Human) 
2026-07-28 | PXD073479 | Pride
Faf2 Hdx-ms P97 
GenomicsThe essential clathrin adaptor protein complex-2 is tumor suppressive specifically in vivo [CRISPR Screen]
The essential clathrin adaptor protein complex-2 is tumor suppressive specifically in vivo [CRISPR Screen]
PRJNA1224449 | ENA
ProteomicsMapping the protein interaction network of adaptor protein complex in Arabidopsis identifies P34 as a common stability regulator
Adaptor protein (AP) complexes are evolutionarily conserved vesicle transport regulators that recruit coat proteins, membrane cargos and coated vesicle accessory proteins. Since in plants endocytic and post-Golgi trafficking intersect at the trans-Golgi network, unique mechanisms for sorting cargos ...
ORGANISM(S): Arabidopsis thaliana (Mouse-ear cress) 
2023-12-07 | PXD035454 | Pride
Ap-ms Arabidopsis Turboid Proximity labeling Adaptor complex Tap Interaction network 
UnknownThe fifth adaptor protein complex.
Not available
S-EPMC3191125 | biostudies-literature
TranscriptomicsDGCR8 acts as a novel adaptor for the exosome complex to degrade double-stranded structured RNAs
The Microprocessor complex (DGCR8/Drosha) is required for microRNA (miRNA) biogenesis but also binds and regulates the stability of several types of cellular RNAs. Of particular interest, DGCR8 controls the stability of mature small nucleolar RNA (snoRNA) transcripts independently of Drosha, suggest...
ORGANISM(S): Homo sapiens 
2015-12-10 | E-GEOD-73376 | biostudies-arrayexpress
UnknownCharacterization of the adaptor-related protein complex, AP-3.
Not available
S-EPMC2139840 | biostudies-literature
Sort   by:  
 Page size