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ADGRG1/GPR56 knockdown in cord blood CD34+ cells
Adgrg1 is a New Transcriptional Target of Hand1 During Trophoblast Giant Cell Differentiation
Adhesion G protein-coupled receptor ADGRG1 promotes protective microglial response in Alzheimer’s disease
The placenta, forming the maternal–fetal interface, is essential for the survival and development of the fetus. It has been shown that the basic helix-loop-helix (bHLH) transcription factor Hand1 plays an important role in trophoblast giant cells (TGCs) differentiation during placental development i...
ORGANISM(S): Mus musculus 
2022-01-12 | GSE193214 | GEO
ADGRG1/GPR56 was knocked down by two different shRNAs in cord blood CD34+ cells via lentiviral transduction. GFP was used as marker indicating successful transduction.
ORGANISM(S): Homo sapiens 
2022-02-06 | GSE150175 | GEO
RNA seq analysis of Gpr56/Adgrg1 expressing 4T1 and TS/A cells cultured with type III collagen
G protein-coupled receptor 56 (GPR56/ADGRG1) is an adhesion GPCR with an essential role in brain development and cancer. Elevated expression of GPR56 was observed in the clinical specimens of Glioblastoma (GBM), a highly invasive primary brain tumor. However, we found the expression to be variable a...
ORGANISM(S): Homo sapiens (Human) 
2022-05-04 | PXD031569 | Pride
Germline genetic architecture of Alzheimer's disease (AD) indicates microglial mechanisms of disease susceptibility and outcomes. However, the mechanisms enabling protective microglial responses remain elusive. Here, we investigate the role of microglial ADGRG1, an adhesion G-protein-coupled recepto...
ORGANISM(S): Mus musculus 
2025-07-25 | GSE273690 | GEO
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