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We applied direct conversion of normal human dermal fibroblast (NHDF) into adipocyte-like cells using adipogenic cocktail containing IBMX, dexamethasone, insulin, and rosiglitazone and confirmed prominent lipid droplet accumulation in the converted cells for proteomic research
ORGANISM(S): Homo sapiens (Human) 
2025-05-13 | PXD050528 | Pride
This study investigated the lipidomic remodeling of Scd1- and Scd2-deficient C2C12 cells during brown adipogenic differentiation. Scd1 or Scd2 knockout cells and corresponding control cells were induced to undergo brown adipocyte-like differentiation for 96 h. To evaluate whether exogenous monounsat...
2026-06-23 | MTBLS14692 | MetaboLights
Attainment of a brown adipocyte cell phenotype in white adipocytes, with their abundant mitochondria and increased energy expenditure potential, is a legitimate strategy for combating obesity. The unique transcriptional regulators of the primary brown adipocyte phenotype are unknown, limiting our ab...
ORGANISM(S): Mus musculus 
Coactosin-like F-actin Binding Protein (Cotl1) Plays a Key Role in Adipocyte Differentiation and Obesity
An Adipocyte-like Signature in Ovarian Cancer Minimal Residual Disease Identifies Metabolic Vulnerabilities of Tumor Initiating Cells
The Adipocyte acquires a Fibroblast-like Transcriptional Signature in response to a High Fat Diet.
Here we show through genome-wide binding studies that transcription factor 7-like 1 (TCF7L1) represses structure-related genes during adipogenesis. Intriguingly, TCF7L1 is induced in a cell contact-dependent manner by confluency in preadipocytes and is required for adipocyte differentiation by repre...
ORGANISM(S): Mus musculus 
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