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MetabolomicsArsenic induces metabolome remodeling in mature human adipocytes
Human lifetime exposure to arsenic through drinking water, food supply or industrial pollution leads to its accumulation in many organs such as liver, kidneys, lungs or pancreas but also adipose tissue. Recently, population-based studies revealed the association between arsenic exposure and the deve...
2025-05-23 | MTBLS8808 | MetaboLights
MetabolomicsCadmium acute exposure induces metabolic and transcriptomic perturbations in human mature adipocytes
Obesity is considered as a major public health concern with strong economic and social burdens. Exposure to pollutants such as heavy metals can contribute to the development of obesity and its associated metabolic disorders, including type 2 diabetes and cardiovascular diseases. Adipose tissue is an...
2023-06-29 | MTBLS4128 | MetaboLights
MetabolomicsMulti-omics analysis of thermogenic lipolysis in brown adipocytes

The integration of omics technologies into molecular biological research has transformed it into a field where a system can be investigated as a whole by combining information from multiple biochemical layers. This extension of traditional molecular biology, where various data sources are conside...

2025-11-12 | MTBLS12307 | MetaboLights
MetabolomicsMTCH2 modulates CPT1 activity to regulate lipid metabolism of adipocytes

To understand the molecular changes that underwrite enhanced mitochondrial respiration upon MTCH2 knockdown, we performed lipidomics profiling in hMADs adipocytes.

2025-08-04 | MTBLS12815 | MetaboLights
MetabolomicsLipidomics of brown adipocytes treated with d9-choline
Not available
ORGANISM(S): Mus musculus 
ST001960 | MetabolomicsWorkbench
MetabolomicsMitochondrial Transplantation of Brown Adipocytes Interferes with the Metabolism of Tumor Stem Cells and Inhibits the Recurrence of Brain Glioma after Operation

Glioblastoma multiforme (GBM) is highly aggressive, with treatment resistance and recurrence driven by metabolically plastic glioma stem cells (GSCs). Inspired by brown adipose tissue (BAT) thermogenesis, researchers transplanted BAT-derived mitochondria (BA-Mito) into GSCs, reducing stemness mar...

2025-08-27 | MTBLS12901 | MetaboLights
MetabolomicsThe Role of Obesity and Adipocytes in Immune Activation on Antiretroviral Therapy
Not available
ORGANISM(S): Homo sapiens 
ST000250 | MetabolomicsWorkbench
TranscriptomicsExpression Data from Bone Marrow Progenitor-Derived Adipocytes, White Adipocytes and Brown Adipocytes.
We have identified a population of adipocytes in fat tissue that arise from bone marrow-derived progenitor cells. We used microarrays to compare the global gene expression patterns of the bone marrow progenitor-derived adipocytes as well as conventional white and brown adipocytes to evaluate the rel...
ORGANISM(S): Mus musculus 
2010-01-08 | E-GEOD-19757 | biostudies-arrayexpress
TranscriptomicsRNA-seq comparison of primary mouse classical brown, beige, and white adipocytes
Classical brown adipocytes in interscapular BAT (Myf-5 derived) and inducible beige cells in WAT (non-Myf-5 derived) have distinct developmental origins, although both cell types have morphological and biochemical characteristics of brown fat such as the expression of UCP1. This raises an important ...
ORGANISM(S): Mus musculus 
2015-03-16 | E-MTAB-2624 | biostudies-arrayexpress
TranscriptomicsGene expression analysis of cultured adipocytes treated with different types of asbestos fibers
We hypothesized that adipocytes can be triggered by asbestos fibers to produce an inflammatory response. Microarray-based gene expression analysis was thus carried out to identify potential inflammation-related candidates with altered expression in adipocytes following asbestos exposure. We found ch...
ORGANISM(S): Mus musculus 
2013-09-03 | E-GEOD-42330 | biostudies-arrayexpress
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