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TranscriptomicsModel-driven multi-omic data analysis elucidates metabolic immunomodulators of macrophage activation
We used genome-scale modeling and multi-omics (transcriptomics, proteomics, and metabolomics) analysis to assess metabolic features that are critical for macrophage activation. We constructed a genome-scale metabolic network for the RAW 264.7 cell line to determine metabolic modulators of activation...
ORGANISM(S): Mus musculus 
2012-08-02 | E-GEOD-39785 | biostudies-arrayexpress
ModelsThiele2011 - Genome-scale metabolic network of Salmonella Typhimurium (STM_v1_0)
Thiele2011 - Genome-scale metabolic network of Salmonella Typhimurium (STM_v1_0) This model is described in the article: A community effort towards a knowledge-base and mathematical model of the human pathogen Salmonella Typhimurium LT2. Thiele I, Hyduke DR, Steeb B, Fankam ...
2015-07-30 | MODEL1507180017 | BioModels
MetabolomicsA polyamine-centric blood-based metabolite panel predictive of poor response to CAR T-cell therapy in large B cell lymphoma

Anti-CD19 chimeric antigen receptor (CAR) T-cell therapy for relapsed or refractory (r/r) large B-cell lymphoma (LBCL) results in durable response in only a subset of patients. MYC overexpression in LBCL tumors is associated with poor response to treatment. We tested whether a MYC-driven polyamin...

2022-10-31 | MTBLS5381 | MetaboLights
UnknownVitamin E Acetate in Bronchoalveolar-Lavage Fluid Associated with EVALI.
Not available
S-EPMC7032996 | biostudies-literature
UnknownAntibody blockade of the Cripto CFC domain suppresses tumor cell growth in vivo.
Not available
S-EPMC171388 | biostudies-literature
UnknownGenome-Wide Association Study of Suicide Death and Polygenic Prediction of Clinical Antecedents.
Not available
S-EPMC7872505 | biostudies-literature
UnknownDiaci v3.0: chromosome-level assembly, de novo transcriptome, and manual annotation of Diaphorina citri, insect vector of Huanglongbing.
Not available
S-EPMC11659978 | biostudies-literature
UnknownCetuximab plus platinum-based chemotherapy in head and neck squamous cell carcinoma: a randomized, double-blind safety study comparing cetuximab produced from two manufacturing processes using the EXTREME study regimen.
Not available
S-EPMC4714495 | biostudies-literature
UnknownRefining the scope of genetic influences on alcohol misuse through environmental stratification and gene-environment interaction.
Not available
S-EPMC11661684 | biostudies-literature
TranscriptomicsLPS treatment of RAW2647 macrophages
Macrophages are central players in the immune response and manifest divergent phenotypes to control inflammation and innate immunity. Signaling factors are traditionally recognized as the stimuli governing macrophage functions. In recent years, metabolism’s importance has been reemphasized as critic...
ORGANISM(S): Mus musculus 
2012-01-24 | E-GEOD-35237 | biostudies-arrayexpress
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