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TranscriptomicsDifferential gene expression in adrenal medulla after cardiac pressure overload
Transcriptom analysis of microdissect adrenal medulla after 8 weeks of cardiac pressure overload caused by transverse aortic constriction. Comparative transcriptome analysis was determined using the GeneChip Mouse Genome 430 2.0 Array (Affymetrix, Santa Clara, CA, USA). Six microarrays from microdis...
ORGANISM(S): Mus musculus 
2011-05-03 | E-GEOD-21829 | biostudies-arrayexpress
TranscriptomicsDH06 Adrenal ACTH Sus scrofa
Large White and Meishan pigs were either non-treated or injected with mammalian 1-24 ACTH (Immediate Synachten, Novartis France) at the dose of 250 µg per animal. Pigs were sacrificed either immediately after capture from their home cage (non-treated animals) or 1 hour following ACTH injection. Adr...
ORGANISM(S): Sus scrofa 
2010-06-29 | E-GEOD-8377 | biostudies-arrayexpress
ProteomicsProteomic analysis of the extracellular matrix in the porcine adrenal cortex
The extracellular matrix (ECM) is a complex network of proteins that provides structural support and influences tissue boundaries, biomechanical properties, and cell polarity. This study analyzed the ECM profile of the porcine adrenal cortex's outer (OF = capsule + subcapsular + zona glomerulosa cel...
ORGANISM(S): Sus scrofa domesticus (domestic pig) 
2025-07-14 | PXD055486 | Pride
Adrenal cortex Extracellular matrix Adrenal gland Porcine 
TranscriptomicsGenome wide analysis of Adrenal Gland tissue from Gata6 conditional knockout versus Control Adrenal tissue
Transcription factor GATA6 is expressed in the fetal and adult adrenal cortex and has been implicated in steroidogenesis. To characterize the role of GATA6 in adrenocortical development and function, we generated mice in which Gata6 was conditionally deleted using Cre-LoxP recombination with Sf1-cre...
ORGANISM(S): Mus musculus 
2013-06-06 | E-GEOD-40398 | biostudies-arrayexpress
TranscriptomicsSingle-nucleus and spatial transcriptome reveal adrenal homeostasis in normal and tumoural adrenal glands
The human adrenal glands are highly dynamic endocrine organs that are involved in the secretion of various hormones such as steroids and catecholamines. Here we present a single-nuclei and spatial transcriptomic analysis of healthy adult human adrenal glands to provide a complete adrenal gland atlas...
ORGANISM(S): Homo sapiens 
2023-01-01 | E-MTAB-12129 | biostudies-arrayexpress
TranscriptomicsAdrenal gland gene expression from adult (12-week old) hypertensive BPH and adult (12-week old) hypotensive BPL mice
The objective of the experiment is to determine the genes differentially expressed in the adrenal gland of adult (12-week) BPH and BPL mice. Adrenal glands from adult (12-week) hypertensive BPH mice (n=3) and adult (12-week) hypotensive BPL mice (n=3).
ORGANISM(S): Mus musculus 
2010-06-16 | E-GEOD-19342 | biostudies-arrayexpress
ProteomicsMass spectrometry-based proteomics discovery of prognostic biomarkers in adrenal cortical carcinoma
Adrenal cortical carcinoma (ACC) is an extremely rare disease with a variable prognosis. Current prognostic markers have limitations in identifying patients with a poor prognosis. Herein, we aimed to investigate the prognostic protein biomarkers of ACC using mass-spectrometry-based proteomics. We pe...
ORGANISM(S): Homo sapiens (Human) 
2021-09-07 | PXD027404 | Pride
Human Ffpe Lfq Adrenal cortical carcinoma Biomarkers 
TranscriptomicsTranscription profiling of Macaca mulatta adrenal gland over a 24 hour period to investigate circadian regulation of gene expression
Circadian regulation of gene expression in central and peripheral tissue has been studied in mice. The biomedical implications of this findings led us to the development of a model in which to study the circadian mechanisms underlying primate physiology. The objective of this experiment has been to ...
ORGANISM(S): Macaca mulatta 
2007-10-05 | E-GEOD-2703 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of rat adrenal zona glomerulosa cells stimulated with aldosterone secretagogues
The mineralocorticoid aldosterone mainly produced by the adrenal gland is essential for life but an abnormal excessive secretion causes severe pathological effects including hypertension and target organ injury in the heart and kidney. The aim of this study was to determine the gene regulatory netwo...
ORGANISM(S): Rattus norvegicus 
2008-10-18 | E-GEOD-8421 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mouse adrenal gland from Wildtype and Per2Cry1 double mutant mice - time series
This SuperSeries is composed of the following subset Series:; GSE4238: rhythmic transcriptome in the murine wt adrenal; GSE4239: Transcriptome regulation in the adrenal gland of circadian clock deficient Per2Cry1 double mutant mice Experiment Overall Design: Refer to individual Series
ORGANISM(S): Mus musculus 
2008-06-20 | E-GEOD-4253 | biostudies-arrayexpress
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