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ProteomicsA safe alternative to H37Rv: the attenuated double auxotroph Mycobacterium tuberculosis ΔleuDΔpanCD
Currently available model organisms such as Mycobacterium smegmatis and Mycobacterium bovis Bacillus Calmette-Guérin (BCG) have significantly contributed to our understanding of tuberculosis (TB) biology, these models have limitations such as differences in genome size, growth rates and virulence. A...
ORGANISM(S): Mycobacterium tuberculosis 
2019-07-30 | PXD013677 | Pride
Biosafety level 2 Model organism Mycobacterium tuberculosis Attenuated auxotroph 
ProteomicsMycobacterium tuberculosis tween supernatants
Tween free supernatants of M. tuberculosis CDC1551, a ppe38-ppe71 knock out mutant and a complemented strain containing tween was used for mass spectrometry and proteomics study to identify the differential regulation of proteins between these strains.
ORGANISM(S): Mycobacterium tuberculosis CDC1551 
2021-06-15 | PXD021168 | Pride
Mycobacterium tuberculosis Lc-ms/ms 
ProteomicsPulse-chase SILAC of Mycobacterium tuberculosis infected THP-1 macrophages
Pulse chase SILAC was used to identify protein turnover within human macrophages infected with mycobacterium tuberculosis CDC1551, a ppe38-71 mutant strain, a complemented strain and an uninfected control.
ORGANISM(S): Homo sapiens (Human) 
2021-06-15 | PXD021166 | Pride
Lc-ms/ms Tuberculosis Silac Macrophages 
ProteomicsMycobacterium tuberculosis tween supernatants
Whole cell lysates of THP-1 macrophages infected with of M. tuberculosis CDC1551, a ppe38-ppe71 knock out mutant and a complemented strain was performed at 4h and 18h post infection to find the differentially regulated proteins.
ORGANISM(S): Homo sapiens (Human) 
2021-06-15 | PXD021167 | Pride
Mycobacterium tuberculosis Lc-ms/ms 
ProteomicsMycobacterium tuberculosis whole cell lysates
Proteomics on whole cell lysates from Mycobacterium tuberculosis CDC1551, a ppe38-ppe71 deletion mutant and a complemented strain grown in modified sautons medium till mid logarithmic phase
ORGANISM(S): Mycobacterium tuberculosis CDC1551 
2021-06-15 | PXD020814 | Pride
Mycobacterium tuberculosis Whole cell lysate Lc-ms/ms 
ProteomicsMycobacterium tuberculosis tween supernatants
Supernatants of M. tuberculosis CDC1551, a ppe38-ppe71 knock out mutant and a complemented strain containing tween was used for mass spectrometry and proteomics study to identify the differential regulation of proteins between these strains.
ORGANISM(S): Mycobacterium tuberculosis CDC1551 
2021-06-15 | PXD020813 | Pride
Mycobacterium tuberculosis Lc-ms/ms 
UnknownInequalities in successful tobacco cessation and tobacco cessation attempts: Evidence from eight Sub-Saharan African countries.
Not available
S-EPMC9681111 | biostudies-literature
ProteomicsInvestigating the protein-protein interactions of EccA3 in Mycobacterium smegmatis
Mycobacterium smegmatis encodes three ESX secretion systems, ESX-1, -3 and -4. Previous research has suggested localisation of the ESX-1 secretion system at the growing polar region of M. smegmatis. In a seperate study, we demonstrated unipolar localisation of EccA3 from ESX-3 at the growing polar r...
ORGANISM(S): Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155) Bacteria 
2022-06-09 | PXD018978 | Pride
Ap-ms Esx Mycobacterium smegmatis Polar localisation 
ProteomicsPlasmodium parasite proteomics of iron deficiency
Iron deficiency anaemia and Plasmodium infection represent significant global health challenges with overlapping geographical distributions, particularly affecting pregnant women in Africa. Previous evidence suggests complex interactions between iron status and malaria susceptibility. However, the p...
ORGANISM(S): Plasmodium falciparum (isolate 3D7) 
2026-01-13 | PXD064348 | Pride
Plasmodium Dfo Proteomics Iron deficiency 
ProteomicsCulture filtrate of Mycobacterium tuberculosis clinical isolate S169
Phagosome acidification is one of the challenges faced by Mycobacterium tuberculosis during infection. This intracellular pathogen is known to adapt to its stressful environment though stress response pathways and by secreting proteins to modify the host immune response for survival and proliferatio...
ORGANISM(S): Mycobacterium tuberculosis 
2025-10-04 | PXD068720 | Pride
Acid stress Tuberculosis Heterogenous Persister Vbnr Tb 
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