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UnknownNew records of the dolphin Albertocetus meffordorum (Odontoceti: Xenorophidae) from the lower Oligocene of South Carolina: Encephalization, sensory anatomy, postcranial morphology, and ontogeny of early odontocetes.
Not available
S-EPMC5695589 | biostudies-literature
ProteomicsProtein Contaminants Matter: Building Universal Protein Contaminant Libraries for DDA and DIA Proteomics
Mass spectrometry-based proteomics is challenged by the presence of contaminant background signals. In particular, protein contaminants from reagents and sample handling are often abundant and almost impossible to avoid, reducing the sensitivity, specificity and reproducibility of protein identifica...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) Mus Musculus (ncbitaxon:10090) 
2022-01-21 | MSV000088714 | MassIVE
ProteomicsBTN2A1 Targeting Reprograms M2-like Macrophages and TAMs via SYK and MAPK Signaling
Tumor-associated macrophages (TAMs), often adopting an immunosuppressive M2-like phenotype, correlate with unfavorable cancer outcomes. Our investigation unveiled elevated expression of the butyrophilin (BTN)2A1 in M2-like TAMs across diverse cancer types. We developed anti-BTN2A1 monoclonal antibod...
ORGANISM(S): Homo sapiens (Human) 
2024-09-02 | PXD055262 | Pride
Lc-msms Ap-ms Butyrophilin (btn)2a1 Reprogramming Mapk Immunosuppressive m2-like Syk Cancer 
ProteomicsProteomic profile of healthy human monocytes differentiated to macrophages with non-tumor or tumor cell-derived extracellular vesicles
To investigate the impact of tumor cell-derived extracellular vesicles on monocyte-macrophage differentiation, healthy monocytes were treated with EVs derived from two different pancreatic cancer cell lines and a non-tumoral pancreatic ductal epithelial cell line. Following differentiation to macrop...
ORGANISM(S): Homo sapiens (Human) 
2026-06-11 | PXD039439 | Pride
Lc-msms Monocytes Tumor-associated macrophages Extracellular vesicles Immunosuppression 
UnknownInteractions of physical activity, muscular fitness, adiposity, and genetic risk for NAFLD.
Not available
S-EPMC9234625 | biostudies-literature
TranscriptomicsCaloric restriction induces heat shock response and inhibits B16F10 cell tumorigenesis both in vitro and in vivo
Caloric restriction (CR) without malnutrition is one of the most consistent strategies for increasing mean and maximal lifespan and delaying the onset of age-associated diseases. Stress resistance is a common trait of many long-lived mutants and life-extending interventions, including CR. Indeed, be...
ORGANISM(S): Mus musculus 
2015-08-06 | E-GEOD-67430 | biostudies-arrayexpress
UnknownNeoadjuvant Chemotherapy Induces Genomic and Transcriptomic Changes in Ovarian Cancer.
Not available
S-EPMC8936832 | biostudies-literature
TranscriptomicsRSD-2 and RSD-6 promote germ cell immortality by repressing spermatogenesis and repeat loci via small interfering RNAs
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Caenorhabditis elegans 
2013-06-01 | E-GEOD-40460 | biostudies-arrayexpress
UnknownTowards cascading genetic risk in Alzheimer's disease.
Not available
S-EPMC11292901 | biostudies-literature
UnknownEnhancing cognitive performance prediction by white matter hyperintensity connectivity assessment.
Not available
S-EPMC11629703 | biostudies-literature
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