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Hypercholesterolemia, the driving force of atherosclerosis, accelerates the expansion and mobilization of hematopoietic stem and progenitor cells (HSPCs). The molecular determinants connecting hypercholesterolemia with hematopoiesis are underexplored. Here we report that a novel somite-derived pro-h...
ORGANISM(S): Mus musculus 
2019-05-23 | GSE122204 | GEO
AIBP-mediated Cholesterol Efflux Instructs Hematopoietic Stem and Progenitor Cell Fate
AIBP-TurboID-HA expressed HUVECs were seaded into 6-well plates. Once they approximately 80% confluence, cells were incubated with biotin-labeling buffer containing 500 umol/L biotin and 200 umol/L ATP. Cell lysate were collected at 6h with or without biotin incubation. The above cell lysate was inc...
ORGANISM(S): Homo sapiens (Human) 
2025-10-07 | PXD056677 | Pride
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