Albert Thomas K TK

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Comparative ChIP-chip analysis of general transcription factor TFIIB and negative cofactor NC2 in human B cells

A comparative ChIP-chip analysis of TFIIB and NC2 in human B cells reveals that basal core promoter architectures control the equilibrium between NC2 and preinitiation complexes. We conducted a comparative ChIP-chip and gene expression analysis of TFIIB in human B cells and analyze associated core p...

ORGANISM(S): Homo sapiens

2010-05-16 | E-GEOD-19562 | biostudies-arrayexpress

Transcription Initiation Platforms and GTF recruitment at tissue-specific enhancers and promoters

Recent works have shown that RNA Polymerase (Pol) II can be recruited to, and transcribe, distal regulatory regions. Here, we analyzed transcription initiation and elongation through genome-wide localization of Pol II, General Transcription Factors (GTFs) and active chromatin in developing T-cells. ...

ORGANISM(S): Mus musculus

2011-05-20 | E-GEOD-29362 | biostudies-arrayexpress

In vivo intratumoral heterogeneity in a dish: scalable forebrain organoid models of embryonal brain tumors for high-throughput personalized drug discovery.

Not available

S-EPMC12728470 | biostudies-literature

MAPK inhibitor sensitivity scores predict sensitivity driven by the immune infiltration in pediatric low-grade gliomas.

Not available

S-EPMC10374577 | biostudies-literature

ETMR stem-like state and chemo-resistance are supported by perivascular cells at single-cell resolution.

Not available

S-EPMC12198369 | biostudies-literature

Clinical characteristics, racial inequities, and outcomes in patients with breast cancer and COVID-19: A COVID-19 and cancer consortium (CCC19) cohort study.