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TranscriptomicsRNA-sequencing of human induced pluripotent stem cell-derived intestinal epithelial organoids
The purpose of this study was to characterise iPSC-derived human intestinal epithelial organoids (iPSCo) by comparing these cultures with primary purified intestinal epithelial cells (IEC). Intestinal epithelial organoid (IEO) cultures were derived from at least three different lines of iPSCs, RNA ...
ORGANISM(S): Homo sapiens 
2018-10-22 | E-MTAB-7306 | biostudies-arrayexpress
TranscriptomicsDNA-methylation profiling of human induced pluripotent stem cell -derived intestinal epithelial organoids
The purpose of this study was to characterise iPSC-derived human intestinal epithelial organoids (iPSCo) by comparing these cultures with primary purified intestinal epithelial cells (IEC). Intestinal epithelial organoid (IEO) cultures were derived from at least three different lines of iPSCs, DNA ...
ORGANISM(S): Homo sapiens 
2018-10-23 | E-MTAB-7289 | biostudies-arrayexpress
UnknownAccelerated methotrexate, vinblastine, doxorubicin, and cisplatin is safe, effective, and efficient neoadjuvant treatment for muscle-invasive bladder cancer: results of a multicenter phase II study with molecular correlates of response and toxicity.
Not available
S-EPMC4050203 | biostudies-literature
TranscriptomicsExpression data from F344N rats in long and short photoperiods
Rats were housed in either long day (LD, 16:8 hours, light:dark) or short day (SD, 8:16 hours, light dark) photoperiods for 3, 14 and 28 days and brains removed, frozen on dry ice and then hypothalamic arcuate nucleus tissue blocks cut for RNA extraction. At each time point 4 rats were used in each ...
ORGANISM(S): Rattus norvegicus 
2012-02-21 | E-GEOD-27926 | biostudies-arrayexpress
TranscriptomicsSingle-cell sequencing of developing human gut reveals transcriptional links to childhood Crohn’s disease
In this study, we performed single-cell transcriptional profiling of human embryonic and fetal gut samples obtained from 9 human embryos spanning ages 6-10 PCW and three regions (duo-jejunum, ileum and colon). Additionally, we profile mucosal biopsies from the terminal ileum of healthy children aged...
ORGANISM(S): Homo sapiens 
2020-12-22 | E-MTAB-8901 | biostudies-arrayexpress
TranscriptomicsPurified intestinal epithelial cells from foetal and paediatric gut
CD326+ sorted intestinal epithelial cells from foetal (9-12 wk gestational age) small bowel and large bowel, CD326+ sorted intestinal epithelial cells from mucosal biopsies of paediatric (5-15 years of age) terminal illeum, ascending colon and sigmoid colon FPG=Foetal proximal gut, FDG=Foetal distal...
ORGANISM(S): Homo sapiens 
2015-09-15 | E-MTAB-3703 | biostudies-arrayexpress
TranscriptomicsPurified intestinal epithelial cells from foetal and paediatric gut
CD326+ sorted intestinal epithelial cells from foetal (9-12 wk gestational age) small bowel and large bowel, CD326+ sorted intestinal epithelial cells from mucosal biopsies of paediatric (5-15 years of age) terminal illeum, ascending colon and sigmoid colon FPG=Foetal proximal gut, FDG=Foetal distal...
ORGANISM(S): Homo sapiens 
2015-09-15 | E-MTAB-3704 | biostudies-arrayexpress
UnknownArchaeosine Modification of Archaeal tRNA: Role in Structural Stabilization.
Not available
S-EPMC7099136 | biostudies-literature
TranscriptomicsRNA-sequencing of coding RNA from human purified intestinal epithelial samples and organoids derived from foetal and paediatric small and large intestine
Human intestinal epithelial organoids (IEO) culture models are rapidly emerging as novel experimental tools to investigate fundamental aspects of intestinal epithelial (patho)physiology. Cellular source and culture protocols vary between different IEO models and reliable markers for their characteri...
ORGANISM(S): Homo sapiens 
2018-01-20 | E-MTAB-5015 | biostudies-arrayexpress
TranscriptomicsDNA methylation array of human purified intestinal epithelial samples and organoids from paediatric and foetal small and large intestine
Human intestinal epithelial organoids (IEO) culture models are rapidly emerging as novel experimental tools to investigate fundamental aspects of intestinal epithelial (patho)physiology. Cellular source and culture protocols vary between different IEO models and reliable markers for their characteri...
ORGANISM(S): Homo sapiens 
2017-10-31 | E-MTAB-4957 | biostudies-arrayexpress
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