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ProteomicsA role for the Trim33 ubiquitin ligase in cellular response to replicative stress
Deregulation of RNA polymerase II (RNAPII) by oncoproteins, such as transcription factor Myc, interferes with DNA replication and is a major source of DNA damage and genomic instability. Ubiquitination is a key pathway controlling RNAPII activity via modification of RNAPII subunits or associated re...
ORGANISM(S): Mus musculus (Mouse) 
2023-07-24 | PXD037854 | Pride
Ap. ap-ms. lc-ms. ubiquitination. trim33. e2f4. stress response 
ProteomicsData Set2: Extensive Rewiring of the EGFR Network in Colorectal Cancer Cells Expressing Transforming Levels of KRASG13D
RAW files of corresponding Baits used in Extensive Rewiring of the EGFR Network in Colorectal Cancer Cells Expressing Transforming Levels of KRASG13D
ORGANISM(S): Homo sapiens (Human) 
2019-12-03 | PXD016461 | Pride
Egfr pathway Interactomic Silac Proteins network Hke-3 Hct-116 
ProteomicsExtensive Rewiring of the EGFR Network in Colorectal Cancer Cells Expressing Transforming Levels of KRASG13D
RAW files of corresponding Baits used in Extensive Rewiring of the EGFR Network in Colorectal Cancer Cells Expressing Transforming Levels of KRASG13D
ORGANISM(S): Homo sapiens (Human) 
2019-12-02 | PXD016505 | Pride
Egfr pathway Ap-ms Interactomic Silac Proteins network Hke-3 Hct-116 
Proteomics: Extensive Rewiring of the EGFR Network in Colorectal Cancer Cells Expressing Transforming Levels of KRASG13D
RAW files of corresponding Baits used in Extensive Rewiring of the EGFR Network in Colorectal Cancer Cells Expressing Transforming Levels of KRASG13D
ORGANISM(S): Homo sapiens (Human) 
2019-12-03 | PXD016512 | Pride
Egfr pathway Ap-ms Interactomic Silac Proteins network Hke-3 Hct-116 
ProteomicsData Set3: Extensive Rewiring of the EGFR Network in Colorectal Cancer Cells Expressing Transforming Levels of KRASG13D
RAW files of corresponding Baits used in Extensive Rewiring of the EGFR Network in Colorectal Cancer Cells Expressing Transforming Levels of KRASG13D
ORGANISM(S): Homo sapiens (Human) 
2019-12-02 | PXD016462 | Pride
Egfr pathway Ap-ms Interactomic Silac Proteins network Hke-3 Hct-116 
ProteomicsData Set3: Extensive Rewiring of the EGFR Network in Colorectal Cancer Cells Expressing Transforming Levels of KRASG13D
RAW files of corresponding Baits used in Extensive Rewiring of the EGFR Network in Colorectal Cancer Cells Expressing Transforming Levels of KRASG13D
ORGANISM(S): Homo sapiens (Human) 
2019-12-03 | PXD016463 | Pride
Egfr pathway Ap-ms Interactomic Silac Proteins network Hke-3 Hct-116 
ProteomicsData Set: Extensive Rewiring of the EGFR Network in Colorectal Cancer Cells Expressing Transforming Levels of KRASG13D
RAW files of corresponding Baits used in Extensive Rewiring of the EGFR Network in Colorectal Cancer Cells Expressing Transforming Levels of KRASG13D
ORGANISM(S): Homo sapiens (Human) 
2019-12-04 | PXD016464 | Pride
Egfr pathway Ap-ms Interactomic Silac Proteins network Hke-3 Hct-116 
ProteomicsExtensive Rewiring of the EGFR Network in Colorectal Cancer Cells Expressing Transforming Levels of KRASG13D
RAW files of corresponding Baits used in Extensive Rewiring of the EGFR Network in Colorectal Cancer Cells Expressing Transforming Levels of KRASG13D
ORGANISM(S): Homo sapiens (Human) 
2019-12-02 | PXD016465 | Pride
Egfr pathway Ap-ms Interactomic Silac Proteins network Hke-3 Hct-116 
ProteomicsExtensive Rewiring of the EGFR Network in Colorectal Cancer Cells Expressing Transforming Levels of KRASG13D
RAW files of full proteome profiling of SILAC labeled HCT 116 and HKE 3 cells
ORGANISM(S): Homo sapiens (Human) 
2019-12-03 | PXD016549 | Pride
Egfr pathway Ap-ms Interactomic Silac Proteins network Hke-3 Hct-116 Proteomic profiling 
ProteomicsExtensive Rewiring of the the Epidermal Growth Factor Receptor EGFR Networks in Colorectal Cancer Cells Expressing Transforming Levels of Oncogenic KRASG13D
Protein-protein-interaction networks (PPINs) organize fundamental biological processes, but how oncogenic mutations impact these interactions and their functions at a network-level scale is poorly understood. Here, we analyze how a common oncogenic KRAS mutation (KRASG13D) affects PPIN structure and...
ORGANISM(S): Homo sapiens (Human) 
2019-12-04 | PXD016431 | Pride
Extensive rewiring of the the epidermal growth factor receptor egfr networks in colorectal cancer cells expressing transforming levels of oncogenic krasg13d 
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