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ProteomicsQuantitative proximity proteomics suggests a phytotransferrin-mediated cell surface-to-chloroplast iron trafficking axis in marine diatoms
Iron is a biochemically critical metal cofactor in enzymes involved in photosynthesis, respiration, nitrate assimilation, nitrogen fixation, and reactive oxygen species defense. Marine microeukaryotes have evolved a phytotransferrin-based iron uptake system to cope with iron scarcity, a major factor...
ORGANISM(S): Phaeodactylum tricornutum (strain CCAP 1055/1) 
2021-03-02 | PXD018022 | Pride
Metal trafficking Proximity proteomics Phytotransferrin Chloroplast Apex2 Endocytosis Ocean Iron cycle Diatoms Phaeodactylum tricornutum 
UnknownRandomized Trial of Hypofractionated, Dose-Escalated, Intensity-Modulated Radiation Therapy (IMRT) Versus Conventionally Fractionated IMRT for Localized Prostate Cancer.
Not available
S-EPMC6804854 | biostudies-literature
TranscriptomicsModulation of murine bone marrow derived dendritic cells by IL-4
The archetypal Th2 cytokine interleukin 4 (IL-4) has previously been shown to alternatively activate dendritic cells (DCs) both in vitro and in vivo.To more fully understand the impact of IL-4 dependent alternative activation of DCs, we used mRNA microarrays to define their transcriptional profile. ...
ORGANISM(S): Mus musculus 
2015-04-28 | E-GEOD-59868 | biostudies-arrayexpress
TranscriptomicsTranscriptional response of the marine pennate diatom Phaeodactylum tricornutum to Fe limitation
Diatoms, which are responsible for up to 40% of the 45 to 50 billion metric tons of organic carbon production each year in the sea, are particularly sensitive to Fe stress. Here we describe the transcriptional response of the pennate diatom Phaeodactylum tricornutum to Fe limitation using a partial ...
ORGANISM(S): Phaeodactylum tricornutum 
2010-05-27 | E-GEOD-8675 | biostudies-arrayexpress
ProteomicsProteome and phosphoproteome response of the diatom Phaeodactylum tricornutum under varying nitrogen and iron
The photosynthetic model marine diatom Phaeodactylum tricornutum was cultured under conditions varying nitrogen content and availability, or varying iron concentrations over diel cycles to elicit shifts in the proteome and phosphoproteome. For the nitrogen experiments, cells were grown to mid-expone...
ORGANISM(S): Phaeodactylum tricornutum 
2020-04-17 | PXD015059 | Pride
Diatom Iron Diel 
ProteomicsProteome response of the diatom Phaeodactylum tricornutum to short term shifts in nitrogen source and availability.
The photosynthetic model marine diatom Phaeodactylum tricornutum was cultured with varying nitrogen sources and availability to elicit shifts in the proteome. Cells were grown to mid-exponential phase on ammonium (880 uM), collected by centrifugation and resuspended in N-free media for 2 hrs, and sp...
ORGANISM(S): Phaeodactylum tricornutum 
2019-09-25 | PXD015061 | Pride
Nitrogen Nitrite Ammonium Diatom Iron Diel Nitrate 
UnknownImproving discharge care: the potential of a new organisational intervention to improve discharge after hospitalisation for acute stroke, a controlled before-after pilot study.
Not available
S-EPMC5629649 | biostudies-literature
UnknownMulti-Institutional Phase II Study of High-Dose Hypofractionated Proton Beam Therapy in Patients With Localized, Unresectable Hepatocellular Carcinoma and Intrahepatic Cholangiocarcinoma.
Not available
S-EPMC4872014 | biostudies-literature
TranscriptomicsRNA-seq of mouse alveolar macrophages from control and Influenza A virus infected animals
Based on the observations that influenza infection led to behavioral changes in alveolar macrophages (AMs), we performed an RNAseq experiment to delineate global gene expression changes that occurred in the AM population after influenza infection versus a control (non-infected) population.
ORGANISM(S): Mus musculus 
2020-08-31 | E-MTAB-9429 | biostudies-arrayexpress
UnknownAdjuvant combined-modality therapy for stage IIIC endometrioid and non-endometrioid endometrial cancer.
Not available
S-EPMC7523189 | biostudies-literature
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