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MetabolomicsProtein-metabolite interactomics of carbohydrate metabolism reveal regulation of lactate dehydrogenase

Metabolic networks are interconnected and influence diverse cellular processes. The protein-metabolite interactions that mediate these networks are frequently low affinity and challenging to systematically discover. We developed mass spectrometry integrated with equilibrium dialysis for the disco...

2023-08-07 | MTBLS7237 | MetaboLights
ProteomicsMitochondrial alternative NADH dehydrogenases limit ROS, protect chloroplasts and promote survival of reoxygenation in Arabidopsis
Weather extremes are increasing worldwide frequently exposing plants to transient flooding. When floodwaters recede, plants have to cope with increased light intensity and elevated oxygen that favor excessive formation of reactive oxygen species (ROS). We report a novel molecular mechanism that help...
ORGANISM(S): Arabidopsis Thaliana (mouse-ear Cress) 
2022-12-02 | PXD032119 | JPOST Repository
UnknownAlternative NADH dehydrogenase extends lifespan and increases resistance to xenobiotics in Drosophila.
Not available
S-EPMC7056681 | biostudies-literature
UnknownAlternative binding modes in abortive NADH-alcohol complexes of horse liver alcohol dehydrogenase.
Not available
S-EPMC7980771 | biostudies-literature
UnknownNovel mitochondrial complex I-inhibiting peptides restrain NADH dehydrogenase activity.
Not available
S-EPMC6757105 | biostudies-literature
TranscriptomicsTranscription profiling of S. cerevisiae to investigate formaldehyde as source of free-energy during growth on glucose
Previously, it has been demonstrated that formate can be utilized by Saccharomyces cerevisiae as additional energy source using cells grown in a glucose-limited chemostat. Here, we investigated utilization of formaldehyde as co-substrate. Since endogenous formaldehyde dehydrogenase activities were i...
ORGANISM(S): Saccharomyces cerevisiae 
2008-10-18 | E-GEOD-8902 | biostudies-arrayexpress
UnknownExpression of alternative NADH dehydrogenases (NDH-2) in the phytopathogenic fungus Ustilago maydis.
Not available
S-EPMC6134880 | biostudies-literature
ProteomicsCopper metabolism in Naegleria gruberi and its deadly relative Naegleria fowleri.
Although copper is an essential nutrient crucial for many biological processes, an excessive concentration can be toxic and lead to cell death. The metabolism of this two-faced metal must be strictly regulated at the cell level. In this study, we investigated copper homeostasis in two related unicel...
ORGANISM(S): Naegleria fowleri Naegleria gruberi 
2022-05-20 | PXD032745 | Pride
Naegleria gruberi Alternative oxidase Naegleria fowleri Dj-1 Copper Alternative nadh dehydrogenase Ctr copper transporters Etc 
UnknownSynthetic lethality of Mycobacterium tuberculosis NADH dehydrogenases is due to impaired NADH oxidation.
Not available
S-EPMC10120654 | biostudies-literature
UnknownUbiquinone binding site of yeast NADH dehydrogenase revealed by structures binding novel competitive- and mixed-type inhibitors.
Not available
S-EPMC5799168 | biostudies-literature
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