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MetabolomicsRepurposing the orphan drug nitisinone to control the transmission of African trypanosomiasis
Tsetse transmit African trypanosomiasis, which is a disease fatal to both humans and animals. A vaccine to protect against this disease does not exist so transmission control relies on eliminating tsetse populations. Although neurotoxic insecticides are the gold standard for insect control, they neg...
2021-10-06 | MTBLS2166 | MetaboLights
UnknownDepletion of Shine-Dalgarno Sequences Within Bacterial Coding Regions Is Expression Dependent.
Not available
S-EPMC5100845 | biostudies-literature
UnknownA novel framework for evaluating the performance of codon usage bias metrics.
Not available
S-EPMC5805967 | biostudies-literature
UnknownLeveraging genome-wide datasets to quantify the functional role of the anti-Shine-Dalgarno sequence in regulating translation efficiency.
Not available
S-EPMC5303271 | biostudies-literature
ProteomicsExposure of Mycobacterium tuberculosis to thioridazine alters the cell envelope permeability; an alternative mechanism for the synergistic effects with other antibiotics
The emergence of multidrug resistant tuberculosis and the increasing level of resistance urges the search for alternative drugs in treatment. Several neuroleptics, like thioridazine, reveal activity against Mycobacterium tuberculosis. Thioridazine was even successfully applied in compassionate thera...
ORGANISM(S): Mycobacterium tuberculosis H37Rv 
2016-07-06 | PXD001208 | Pride
Proteomics Mycobacterium tuberculosis Thioridazine Lc-ms/ms 
UnknownNo evidence for Fabaceae Gametophytic self-incompatibility being determined by Rosaceae, Solanaceae, and Plantaginaceae S-RNase lineage genes.
Not available
S-EPMC4451870 | biostudies-literature
UnknownCross-evaluation of metrics to estimate the significance of creative works.
Not available
S-EPMC4321294 | biostudies-literature
TranscriptomicsGene expression in CF-vs-non CF human airway epithelial cell samples obtained by nasal brushing.
A small-scale whole genome microarray study of gene expression in human native nasal epithelial cells from F508del-CFTR homozygous CF patients and non-CF controls. We used the custom designed Affymetrix HsAirwaya520108F Arrays to compare gene expression in 5 CF and 5 non CF nasal epithelial cell sam...
ORGANISM(S): Homo sapiens 
2013-04-10 | E-GEOD-40445 | biostudies-arrayexpress
UnknownSocial Influences on Prevotella and the Gut Microbiome of Young Monkeys.
Not available
S-EPMC5547018 | biostudies-literature
ProteomicsClick-linking: a cell-compatible protein crosslinking method based on click chemistry
We developed a novel approach to in situ crosslinking mass spectrometry (XL-MS) where the reaction is split into two sequential and orthogonal coupling events. The method involves pre-stabilization of the proteome using a fixation protocol, followed by a two-step process that begins with extensive l...
ORGANISM(S): Homo sapiens (Human) Escherichia coli 
2025-01-28 | PXD059118 | Pride
In situ Crosslinking Proteome-wide Protein-protein interactions Interactome 
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