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TranscriptomicsTemporal response of DCs to LPS stimulation: 4sU_sequencing
Regulation of RNA levels is critical for the response to external stimuli and determined through the interplay between RNA production, processing and degradation. Despite the centrality of these processes, most global studies of RNA regulation do not distinguish their separate contributions and rela...
ORGANISM(S): Mus musculus 
2011-04-24 | E-GEOD-25432 | biostudies-arrayexpress
TranscriptomicsRNA-Seq global gene expression of four Dendritic cells subpopulations from lung (CD8+ and CD8- pDCs, CD103-CD11b+ and CD103+CD11b- cDCs) of influenza infected mice at four time points following infection
Hundreds of immune cell types work in coordination to maintain tissue homeostasis. Upon infection, dramatic changes occur with the localization, migration and proliferation of the immune cells to first alert the body of the danger, confine it to limit spreading, and finally extinguish the threat and...
ORGANISM(S): Mus musculus 
2014-03-03 | E-GEOD-49932 | biostudies-arrayexpress
TranscriptomicsRNA-Seq global gene expression in lung tissue at ten time points during a 7-day time course of infection
Hundreds of immune cell types work in coordination to maintain tissue homeostasis. Upon infection, dramatic changes occur with the localization, migration and proliferation of the immune cells to first alert the body of the danger, confine it to limit spreading, and finally extinguish the threat and...
ORGANISM(S): Mus musculus 
2014-03-03 | E-GEOD-49933 | biostudies-arrayexpress
TranscriptomicsRNA sequencing of mouse DCs
RNA-Seq data were targeted for de novo assembly and reconstruction of full-length mouse transcripts. Sequencing of RNA taken from unstimulated DCs.
ORGANISM(S): Mus musculus 
2011-05-12 | E-GEOD-29209 | biostudies-arrayexpress
TranscriptomicsEquivalent mutations in the eight subunits of the chaperonin CCT produce dramatically different cell phenotypes.
The eukaryotic cytoplasmic chaperonin-containing TCP-1 (CCT) is a complex formed by two back-to-back stacked hetero-octameric rings that assists the folding of actins, tubulins and other proteins in an ATP-dependent manner. Here, we decided to test the significance of the hetero-oligomeric nature o...
ORGANISM(S): Saccharomyces cerevisiae 
2010-06-30 | E-GEOD-19511 | biostudies-arrayexpress
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