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Eukaryotic chromatin is organised in individual domains, which are defined by their location within the nuclear space and their distinct proteomic compositions. In contrast to cellular organelles surrounded by lipid membranes, the composition of distinct chromatin domains is rather ill described and...
ORGANISM(S): Drosophila melanogaster (Fruit fly) 
2024-05-29 | PXD044295 | Pride
Eukaryotic chromatin is organised in individual domains, which are defined by their location within the nuclear space and their distinct proteomic compositions. In contrast to cellular organelles surrounded by lipid membranes, the composition of distinct chromatin domains is rather ill described and...
ORGANISM(S): Drosophila melanogaster (Fruit fly) 
2024-05-29 | PXD044296 | Pride
Comprehensive proteome analysis of rare cell phenotypes remains a significant challenge. We report a method for low cell number mass spectrometry (MS)-based proteomics using protease digestion of mildly formaldehyde-fixed cells in cellulo, which we call the ‘in-cell digest’. We combined this with AM...
ORGANISM(S): Homo sapiens (Human) 
2021-11-25 | PXD028117 | Pride
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