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ProteomicsAmyloids as protein traps in bladder cancer
Despite the current diagnostic and therapeutic approaches to bladder cancer being widely accepted, there have been few significant advancements in this field over the past decades. This underscores the necessity for a paradigm shift in the approach to bladder cancer. The role of amyloids in cancer r...
ORGANISM(S): Homo sapiens (Human) 
2024-12-19 | PXD053864 | Pride
Cancer Amyloids Aggregation 
ModelsMasel2000 - Drugs to stop prion aggregates and other amyloids
Masel2000 - Drugs to stop prion aggregates and other amyloids Encoded non-curated model. Issues:  - Missing initial concentration for species y, yb and z - Not reproducible figures This model is described in the article: Designing drugs to stop the formation of prion aggregates an...
2015-04-15 | MODEL1410310000 | BioModels
ProteomicsCell membrane proteome analysis in HEK293T cells challenged with α-Synuclein amyloids
Amyloids interact with plasma membranes. Extracellular amyloids cross the plasma membrane barrier. Internalized extracellular amyloids are reported to trigger amyloidogenesis of endogenous proteins in recipient cells. To what extent these extracellular and intracellular amyloids perturb the plasma ...
ORGANISM(S): Homo sapiens (Human) 
2024-07-09 | PXD046280 | Pride
Membrane shaving Internalization Α-synuclein Plasma membrane Amyloids 
ProteomicsAmyloids from WT and mstr C. elegans
200,000 worms were grown to the young adult stage, collected, and washed. Worms were homogenized in lysis buffer (10mM Tris, pH 7.5, 138mM NaCl, 2mM CaCl2, and 0.1% NP-40). After homogenization, 125U/mL Benzonase nuclease was added to homogenates and samples were incubated for 30 mins at room temper...
ORGANISM(S): Caenorhabditis elegans 
2024-07-09 | PXD043926 | Pride
C. elegans Nematode Worm Amyloids 
ProteomicsReversible amyloids of pyruvate kinase couple cell metabolism and stress granule disassembly
Cells respond to stress by blocking translation, rewiring metabolism, and forming transient mRNP assemblies called stress granules (SGs). After stress release, re-establishing homeostasis requires energy-consuming processes. However, the molecular mechanisms whereby cells restore energy production t...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2021-08-17 | PXD026060 | Pride
Srm Cdc19 Aggregation 
GenomicsA enzymatic program that assembles amyloids
A enzymatic program that assembles amyloids
PRJNA976690 | ENA
GenomicsA enzymatic program that assembles amyloids [ePAT]
A enzymatic program that assembles amyloids [ePAT]
PRJNA976695 | ENA
UnknownBiological Amyloids Chemically Damage DNA.
Not available
S-EPMC11803820 | biostudies-literature
UnknownFunctional Amyloids.
Not available
S-EPMC6886451 | biostudies-literature
UnknownTesting Antimicrobial Properties of Selected Short Amyloids
Not available
S-EPMC9821130 | biostudies-literature
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