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Extreme gradient boosting (XGBoost), an efficient and robust machine learning algorithm, was used to develop a model for classifying the IU, VKH, and control groups. The three proteins deemed most important were transferrin (TF), calsyntenin-1 (CLSTN1), and retinol-binding protein 4 (RBP4), which re...
ORGANISM(S): Homo Sapiens 
2023-07-06 | PXD043575 |
We performed liquid chromatography-tandem mass spectrometry-based proteomic methods to evaluate the aqueous humor protein profiles of all 37 samples.
ORGANISM(S): Homo Sapiens 
2023-07-07 | PXD043597 |
The outbreak of coronavirus disease 2019 (COVID-19), which is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has posed a serious threat to global public health. The mechanism of pathogenesis and host immune response to SARS-CoV-2 infection are largely unknown. In the present...
ORGANISM(S): SARS coronavirus GD322 
2021-03-08 | PXD021097 | Pride
In Brucella spp., the type IV secretion system (T4SS) is essential for bacterial intracellular survival and inhibition of the host innate immune response. The Brucella T4SS secretes 15 different effectors to escape host immunity and promote intracellular replication. Among them, BspF has a GNAT-fami...
ORGANISM(S): Brucella sp. 
2021-09-09 | PXD021423 | Pride

Nonalcoholic fatty liver disease (NAFLD) is a major public health problem due to the high incidence affecting approximately one-third of the world’s population. NAFLD is usually linked to obesity and excessive weight. A subset of patients with NAFLD express normal or low body mass index; thus, th...

2024-02-27 | MTBLS9365 | MetaboLights
Uveitis and posterior scleritis are sight-threatening diseases with undefined pathogenesis, accurate diagnosis remains challenging. Here, two plasma-derived extracellular vesicle (EV) subpopulations, small and large EVs, were obtained from patients with uveitis and posterior scleritis and subjected ...
ORGANISM(S): Homo Sapiens 
2022-09-19 | PXD036844 |
Through mass spectrometry to obtain a high-quality mGluR2 interactome, screened host factors interacting with mGluR2. The experiment was repeated three times.
ORGANISM(S): Homo Sapiens 
2022-10-11 | PXD037306 |
The protein samples stored at -80 °C were thawed and treated with lysis buffer (8M urea, 1% protease inhibitor, 50mM NH4HCO3) for 5 minutes in room temperature. After ultrasonic cracking on ice and centrifugation at 14000g for 10 min at 20 °C, the amount of total protein of each MSC sample was detec...
ORGANISM(S): Homo Sapiens 
2023-06-12 | PXD033812 |
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