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MetabolomicsSpermine is a natural suppressor of AR signaling in castration-resistant prostate cancer
In castration-resistant prostate cancer (CRPC), clinical response to androgen receptor (AR) antagonists is limited mainly due to AR-variants expression and restored AR signaling. The metabolite spermine is most abundant in prostate and it decreases as prostate cancer progresses, but its functions re...
2023-10-11 | MTBLS8034 | MetaboLights
UnknownAn embryo of protocells: The capsule of graphene with selective ion channels.
Not available
S-EPMC4437305 | biostudies-literature
ProteomicsDendrobium mixture ameliorates non-alcoholic fatty liver disease induced by type 2 diabetes mellitus through PPAR gamma: an integrated study of bioinformatics analysis and experimental verification
Dendrobium mixture (DM) is a patented Chinese herbal medicine indicated which has anti inflammatory and improved glycolipid metabolism. However, its active ingredients, targets of action, and potential mechanisms are still uncertain. Here, we investigate the role of DM as a prospective modulator of ...
ORGANISM(S): Mus Musculus 
2023-01-28 | PXD039727 |
TranscriptomicsAge Map, Cerebellum (A)
To assess the transcriptional changes in different brain regions and spinal cord associated with aging and either a caloric restricted (CR) or ad libitum (AL) diet. cDNA microarray and quantitative PCR analyses were used to examine the transcriptomes of various neuronal tissues in young, middle aged...
ORGANISM(S): Mus musculus 
2009-06-21 | E-GEOD-8409 | biostudies-arrayexpress
TranscriptomicsRTN1 IS A NOVEL MEDIATOR FOR PROGRESSION OF KIDNEY DISEASE
Gene expression profiling of kidneys from the murine model of HIV-associated nephropathy (HIVAN) identified an association between the expression of an endoplasmic reticulum (ER)-associated protein reticulon-1, RTN1, and the severity of kidney disease. Of the three known RTN1 isoforms, only RTN1A pr...
ORGANISM(S): Mus musculus 
2015-05-20 | E-GEOD-69074 | biostudies-arrayexpress
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