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UnknownCrystal structure of a far-red-sensing cyanobacteriochrome reveals an atypical bilin conformation and spectral tuning mechanism.
Not available
S-EPMC8000052 | biostudies-literature
ProteomicsSpatial Proteomics Profiling of Vascular Smooth Muscle Cells and Atherosclerotic Plaques in a Diabetic Atherosclerosis Mouse Model
This project presents a spatial proteomic investigation of vascular smooth muscle cells (VSMCs) and atherosclerotic plaque regions in a diabetic mouse model of atherosclerosis (DMAS). Using ApoE-/- mice fed with a high-fat diet and treated with low-dose streptozotocin (STZ) to induce a diabetic phen...
ORGANISM(S): Mus musculus (Mouse) 
2025-09-29 | PXD063231 | Pride
Diabetes mellitus  atherosclerosis  spatial proteomic technology 
MetabolomicsIntegration of metabolomics, genomics and immune phenotypes reveals the causal roles of metabolites in disease

BACKGROUND: Recent studies highlight the role of metabolites in immune diseases, but it remains unknown how much of this effect is driven by genetic and non-genetic host factors.

RESULT: We systematically investigate circulating metabolites in a cohort of 5...

2021-06-14 | MTBLS2633 | MetaboLights
UnknownCrystal-on-crystal chips for in situ serial diffraction at room temperature.
Not available
S-EPMC6057835 | biostudies-literature
MetabolomicsHyocholic acid species as novel biomarkers for metabolic disorders
Hyocholic acid (HCA) is a major bile acid (BA) species in the BA pool of pigs, a species known for its exceptional resistance to spontaneous development of diabetic phenotypes. HCA and its derivatives are also present in human blood and urine. We investigate whether human HCA profiles can predict th...
2021-10-06 | MTBLS2343 | MetaboLights
UnknownThe interplay between chromophore and protein determines the extended excited state dynamics in a single-domain phytochrome.
Not available
S-EPMC7368379 | biostudies-literature
UnknownDimer Asymmetry and Light Activation Mechanism in Brucella Blue-Light Sensor Histidine Kinase.
Not available
S-EPMC8092228 | biostudies-literature
UnknownStructural basis of molecular logic OR in a dual-sensor histidine kinase.
Not available
S-EPMC6778262 | biostudies-literature
UnknownMode of autophosphorylation in bacteriophytochromes RpBphP2 and RpBphP3.
Not available
S-EPMC10619329 | biostudies-literature
UnknownA novel mechanism for the protection against acute lung injury by melatonin: mitochondrial quality control of lung epithelial cells is preserved through SIRT3-dependent deacetylation of SOD2.
Not available
S-EPMC11803069 | biostudies-literature
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