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Anal squamous cell carcinoma (ASCC) is an infrequent tumor. Since 70s, treatment of stages II-III consists on a combination of 5-fluorouracil (5FU), mitomycin C (MMC), and radiotherapy. The aim of this study is the identification of biomarkers that allow personalized treatment and improvement of the...
ORGANISM(S): Homo sapiens (Human) 
2023-04-26 | PXD037816 | Pride
Etiologically linked to HPV infection, malignancies of the anal canal have substantially increased in incidence over the last 20 years. Although most anal squamous cell carcinomas (SCC) respond well to chemoradiotherapy, for undetermined reasons, a subgroup of patients experience a poor outcome. Des...
ORGANISM(S): Homo sapiens (Human) 
2016-12-20 | PXD004859 | Pride
Anal Squamous Cell Carcinoma (ASCC) Exome Sequencing
Inflammatory pathways confer resistance to chemoradiotherapy in anal squamous cell carcinoma
Gene expression profile of squamous lung cancer cells are used to identify genes that are differentially regulated. Experiment Overall Design: Each pair of samples represent a single patient with squamous lung cancer. One is derived from the cancer cells, and the other is from the normal cells. Fi...
ORGANISM(S): Homo sapiens 
Genome and transcriptome sequence data from a squamous cell carcinoma of anal canal patient, generated as part of the BC Cancer Agency's Personalized OncoGenomics (POG) study
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