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ProteomicsIP-MS Profiling of ANAPC1 and MP1 Interaction Networks in OVCAR3 Cells
We identified a pseudogene-derived chimeric transcript, vA-202, which encodes a partial ANAPC1-derived protein (MP1). To characterize its protein interaction network, we transiently expressed FLAG-tagged MP1 in OVCAR3 cells and performed immunoprecipitation using an anti-FLAG antibody. For compariso...
ORGANISM(S): Homo sapiens (Human) 
2026-05-25 | PXD070186 | Pride
Human Mp1 Anapc1 Ip-ms Ovarian cancer 
UnknownElevated expression of ANAPC1 in lung squamous cell carcinoma: clinical implications and mechanisms.
Not available
S-EPMC11951694 | biostudies-literature
UnknownRothmund-Thomson syndrome type 1 caused by biallelic ANAPC1 gene mutations.
Not available
S-EPMC9060067 | biostudies-literature
UnknownMutations in ANAPC1, Encoding a Scaffold Subunit of the Anaphase-Promoting Complex, Cause Rothmund-Thomson Syndrome Type 1.
Not available
S-EPMC6731352 | biostudies-literature
UnknownSequence variation at ANAPC1 accounts for 24% of the variability in corneal endothelial cell density.
Not available
S-EPMC6427039 | biostudies-literature
UnknownAnaphase-Promoting Complex Subunit 1 Associates with Bone Mineral Density in Human Osteoporotic Bone.
Not available
S-EPMC10454667 | biostudies-literature
UnknownThe Potential Biological Roles and Clinical Significance of Anaphase-Promoting Complex Subunit 1 in Colorectal Cancer.
Not available
S-EPMC12033653 | biostudies-literature
TranscriptomicsEffect of depletion of ANAPC1P2 on OVCAR3 cells.
ANAPC1P2 is a chimeric pseudogene that gives rise to a novel chimeric long non-coding transcript, vA-202 (RMND5A-ANAPC1). Notably, vA-202 functions as a γ-irradiation–responsive lncRNA, becoming induced under genotoxic stress conditions. In this study, we generated ANAPC1P2-knockdown OVCAR3 cell lin...
ORGANISM(S): Homo sapiens 
2025-11-26 | GSE311331 | GEO
UnknownRothmund-Thomson syndrome, a disorder far from solved.
Not available
S-EPMC10676203 | biostudies-literature
TranscriptomicsAssociation between blood parameters, whole-blood transcriptomic profiles, and immune-related adverse events in metastatic renal cell carcinoma during nivolumab plus ipilimumab
Pretreatment immune profiles associated with immune-related adverse events (irAEs) may inform individualized management strategies, including enhanced monitoring and early toxicity intervention, in patients with metastatic renal cell carcinoma (mRCC) treated with nivolumab plus ipilimumab. In this c...
ORGANISM(S): Homo sapiens 
2026-02-14 | GSE319496 | GEO
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