Sort   by:  
 Page size 
TranscriptomicsBreast Carcinomas arising at a Young Age: A Unique Biology or a Surrogate for Aggressive Intrinsic Subtypes.
Breast cancer is no longer viewed as a homogenous disease, but rather a compilation of several distinct subtypes as defined by microarray or other large scale genomic analyses. Based on prior reports, we hypothesized that younger women’s breast tumors would be enriched for more aggressive subtypes ...
ORGANISM(S): Homo sapiens 
2010-08-31 | E-GEOD-20624 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human breast tumors to identify age-specific differences of oncogenic pathway deregulation
Breast cancer arising in young women has a poorer prognosis, is less likely to be hormone sensitive, and represents a particularly challenging clinical entity. The biology driving the aggressive nature of breast cancer arising in young women has yet to be defined. Among 784 patients with early stag...
ORGANISM(S): Homo sapiens 
2008-06-15 | E-GEOD-7849 | biostudies-arrayexpress
TranscriptomicsEfficacy of carboplatin alone and in combination with ABT888 in intracranial murine models of BRCA-mutated and BRCA-wild-type triple negative breast cancer
Purpose:Triple negative breast cancer (TNBC) commonly metastasizes to the brain and predicts poor prognosis with limited therapeutic options. TNBC frequently harbors BRCA mutations translating to platinum sensitivity; platinum response may be augmented by additional suppression of DNA repair mechani...
ORGANISM(S): Homo sapiens 
2015-05-12 | E-GEOD-55399 | biostudies-arrayexpress
UnknownBreast carcinomas arising at a young age: unique biology or a surrogate for aggressive intrinsic subtypes?
Not available
S-EPMC3055864 | biostudies-literature
TranscriptomicsDifferentiation Score and Intrinsic Subtype Predict Breast Cancer Organ of Relapse
The ability to predict metastatic potential is of clinical and biological importance. Numerous metastasis/relapse predictors exist for breast cancer patients; however, what is less well established is whether predicting metastasis to specific organs sites is feasible. In this study we sought to dete...
ORGANISM(S): Homo sapiens 
2011-06-20 | E-GEOD-26338 | biostudies-arrayexpress
TranscriptomicsMolecular Characterization of Basal-like and Non-Basal-like Triple-Negative Breast Cancers
Triple-negative (TN) and Basal-like (BL) breast cancer definitions have been used interchangeably to identify breast cancers that lack expression of the hormonal receptors (HR) and overexpression and/or amplification of HER2. However, both classifications when compared to each other, show substantia...
ORGANISM(S): Homo sapiens 
2014-07-29 | E-GEOD-41119 | biostudies-arrayexpress
UnknownGenomic analysis identifies unique signatures predictive of brain, lung, and liver relapse.
Not available
S-EPMC3303043 | biostudies-literature
UnknownBreast Carcinomas arising at a Young Age: A Unique Biology or a Surrogate for Aggressive Intrinsic Subtypes
Not available
ORGANISM(S): Homo sapiens 
S-ECPF-GEOD-20624 | biostudies-other
UnknownDifferentiation Score and Intrinsic Subtype Predict Breast Cancer Organ of Relapse
Not available
ORGANISM(S): Homo sapiens 
S-ECPF-GEOD-26338 | biostudies-other
UnknownAn integration of complementary strategies for gene-expression analysis to reveal novel therapeutic opportunities for breast cancer.
Not available
S-EPMC2750116 | biostudies-literature
Sort   by:  
 Page size