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The oncoprotein survivin, coded by BIRC5 gene has been shown to bind to chromatin. Chromatin immunoprecipitation of stimulated CD4+ T cells with survivin has been published (GSE190354). The role of survivin in transcriptional regulation acting in synergy with transcription factor complexes has been ...
ORGANISM(S): Homo sapiens (Human) 
2025-05-06 | PXD049683 | Pride
The experiment was designed to study the transcriptomic response of the centric diatom Skeletonema marinoi to the presence of cues from the grazer Calanus finmarchicus. Samples were collected in triplicate after 65 and 89 hours of exposure of diatom cells to the copepods. Control samples with no cop...
ORGANISM(S): Skeletonema marinoi 
EndoC-bH1 cells were incubated with control siRNA or PCSK9 siRNA for 72 hours. The experiment was powered based PCSK9 knockdown in the pilot experiment [PXDxxx (PE083)]. Sample size: 12x12.
ORGANISM(S): Homo sapiens (Human) 
2022-04-07 | PXD027913 | Pride
Intact living conduit vessels (umbilical veins) were exposed to normal or high intraluminal pressure, or low or high shear stress in combination with a physiological level of the other force. We used a unique vascular ex vivo perfusion system. After six hours of perfusion endothelial cells were isol...
ORGANISM(S): Homo sapiens 
EndoC-bH1 cells were incubated with control siRNA or PCSK9 siRNA for 72 hours. The experiment was powered based PCSK9 knockdown in a pilot experiment. Sample size: 12x12.
ORGANISM(S): Homo sapiens (Human) 
2022-04-07 | PXD027911 | Pride
EndoC-bH1 cells were incubated with control siRNA or PCSK9 siRNA for 72 hours. Unpowered exploratory experiment. Sample size: 3x3.
ORGANISM(S): Homo sapiens (Human) 
2022-04-07 | PXD027921 | Pride
EndoC-bH1 cells proteomics was assessed in untreated baseline condition and after treatment with control siRNA at 24, 48 and 72 hours. Unpowered exploratory experiment. Sample size: triplicate per condition.
ORGANISM(S): Homo sapiens (Human) 
2022-04-07 | PXD027898 | Pride
EndoC-bH1 cells were incubated with control siRNA or PCSK9 siRNA for 24, 48 and 72 hours. Untreated baseline samples were also included. Unpowered exploratory experiment. Sample size: triplicate per condition.
ORGANISM(S): Homo sapiens (Human) 
2022-04-07 | PXD027920 | Pride
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