Survivin - OmicsDI

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Survivin-expressing advanced/recurrent colorectal cancer patients or patients who refuse standard cancer therapy (1)
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Mass Spectrometry (12)
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UNIPROT ID/AC

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CHEBI ID

CHEBI:68494 (1)
CHEBI:27686 (1)
CHEBI:45713 (1)
CHEBI:15864 (1)
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CHEBI:6584 (1)
CHEBI:2772 (1)
CHEBI:36281 (1)
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Metabolite Name

Luteoforol (1)
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First Public Date

2014 (19)
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2018 (3)
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Modelling Approach

Ordinary differential equation model (1)

Study status

Active, not recruiting (2)

Lab affiliation

1. Wellcome Centre for Cell Biology, University of Edinburgh, Edinburgh EH9 3BF, UK 2. Technical University, Berlin 13355, Germany (1)
Cancer Biology Department, Fox Chase Cancer Center, Philadelphia, PA, USA (1)
Clinical Proteomics (1)
Department of Genetics, Cell Biology and Anatomy, University of Nebraska Medical Center, Omaha, NE 68198, USA (1)
Department of Rheumatology and Inflammation research, Sahlgrenska academy, Gothenburg University, Gothenburg, Sweden (1)
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Faculty of Medicine and Health Sciences School of Life Sciences University of Nottingham NG7 2UH United Kingdom (1)
Genome Integrity Unit, Children's Medical Research Institute, Westmead, Australia, 2145 (1)
National Cancer Institute, NIH Bethesda, MD 20892 (1)
University of Edinburgh (1)
VIB-UGent Center for Medical Biotechnology, VIB, Ghent, Belgium Department of Biomolecular Medicine, Ghent University, Ghent, Belgium (1)
Wellcome Centre for Cell Biology, University of Edinburgh, Edinburgh EH9 3BF, UK; Bioanalytics, Institute of Biotechnology, Technische Universität Berlin, 13355 Berlin, Germany. (1)

IsPrivate

False (1)

Study type

Transcription profiling by array (29)
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Release Date

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Mass spectrometry (LC-MS) of survivin binding proteins immunoprecipitated from human THP1 cells

The oncoprotein survivin, coded by BIRC5 gene has been shown to bind to chromatin. Chromatin immunoprecipitation of stimulated CD4+ T cells with survivin has been published (GSE190354). The role of survivin in transcriptional regulation acting in synergy with transcription factor complexes has been ...

ORGANISM(S): Homo sapiens (Human)

2025-05-06 | PXD049683 | Pride

Survivin ChIPseq

PRJNA786829 | ENA

Expression of survivin in lung eosinophils is associated with pathology in a mouse model of allergic asthma

This SuperSeries is composed of the following subset Series: GSE15345: Expression of survivin in lung eosinophils is associated with pathology in a mouse model of allergic asthma 1 GSE15414: Expression of survivin in lung eosinophils is associated with pathology in a mouse model of allergic asthma 2...

ORGANISM(S): Mus musculus

2010-05-18 | E-GEOD-15429 | biostudies-arrayexpress

Human HEK 293T cells transfected with pEGFP-survivin gene

Transcriptional profiling of human embryonic kidney 293 cells comparing transfected control pEGFP-C1 (empty vector) with pEGFP (survivin vector). One condition experiment; survivin transfected cell as test sample vs empty vector transfected cell as reference; one dye swap replicate

ORGANISM(S): Homo sapiens

2014-10-21 | E-GEOD-43817 | biostudies-arrayexpress

Transcription profiling of breast cancer cells stably expressing survivin

comparison of gene expression in MCF-7 and MCF-7 survivin cells

ORGANISM(S): Homo sapiens

2009-05-19 | E-MEXP-2184 | biostudies-arrayexpress

USP1 expression driven by EWS-FLI1 transcription factor stabilizes Survivin and promotes Ewing sarcoma cell survival

Ewing sarcoma (EWS) is a malignant pediatric bone cancer. Most Ewing sarcomas are driven by EWS-FLI1 oncogenic transcription factor that plays roles in transcriptional regulation, DNA damage response, cell cycle checkpoint control, and alternative splicing. USP1, a deubiquitylase which regulates DNA...

ORGANISM(S): Homo sapiens (Human)

2024-01-26 | PXD041033 | Pride

Ews-fli1 Usp1 Survivin

Expression of survivin in lung eosinophils is associated with pathology in a mouse model of allergic asthma 1

Humans vary markedly in their propensity to develop asthma, despite often being exposed to similar environmental stimuli. Similarly, mouse strains vary in susceptibility to airways pathology in experimental asthma. Sensitization and aerosol challenge with ovalbumin (OVA) induces eosinophil accumulat...

ORGANISM(S): Mus musculus

2010-05-18 | E-GEOD-15345 | biostudies-arrayexpress

Expression of survivin in lung eosinophils is associated with pathology in a mouse model of allergic asthma 2

ORGANISM(S): Mus musculus

2010-05-18 | E-GEOD-15414 | biostudies-arrayexpress

Mutant p53 regulates survivin to foster lung metastasis

PRJNA601320 | ENA

Survivin promotes stem cell competence for skin cancer initiation [scRNA-seq]

PRJNA1162800 | ENA

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