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ProteomicsProteomic analysis of polysomes isolated from human cells infected with polio, zika or dengue viruses
Viral pathogens are an ongoing threat to public health worldwide. Dissecting their dependence on host biosynthetic pathways could lead to effective antiviral therapies. To define how entero- and flaviviruses redirect host ribosomes to synthesize viral proteins and disable host protein production, we...
ORGANISM(S): Homo sapiens (Human) 
2021-08-17 | PXD024546 | Pride
Lc-ms/ms Ribosomes Viruses Polysomes Human Infection Protein synthesis Proteostasis Protein folding Translation 
TranscriptomicsGenome-wide analysis of Dengue virus 2 infected cells
The goal of this study was to compare the transcriptional profile (RNA-seq) of Dengue virus 2 and mock infected cells at 24 and 36 hours post infection. Dengue virus NS5 protein plays multiple functions in the cytoplasm of infected cells, enabling viral RNA replication and counteracting host antivir...
ORGANISM(S): Homo sapiens 
2016-08-09 | E-GEOD-84285 | biostudies-arrayexpress
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