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Cyclic dipeptides are produced by organisms across all domains of life, with many exhibiting anticancer and antimicrobial properties. Oxidations are often key to their biological activities, particularly C-C bond oxidation catalyzed by tailoring enzymes including cyclodipeptide oxidases. These flavi...
ORGANISM(S): Nocardiopsis dassonvillei 
2025-01-06 | PXD058613 | Pride
ATRX safeguards cellular identity during C. elegans development
The objective of the experiment was to determine the impact of cap-adjacent 2'-O-ribose methylation on steady-state mRNA levels in a background lacking the decapping exonculease EOL-1. We depleted CMTR-1 protein, which is the main enzyme responsible for of cap-adjacent 2'-O-ribose methylation in C. ...
ORGANISM(S): Caenorhabditis elegans 
The objective of the experiment was to determine the impact of cap-adjacent 2'-O-ribose methylation on steady-state mRNA levels. We depleted CMTR-1 protein, which is the main enzyme responsible for of cap-adjacent 2'-O-ribose methylation in C. elegans. This was achieved using animals homozygous for ...
ORGANISM(S): Caenorhabditis elegans 
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