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UnknownGlobal topology analysis of pancreatic zymogen granule membrane proteins.
Not available
S-EPMC2596344 | biostudies-literature
TranscriptomicsChromatin immunoprecipitation to determine DNA methylation of mouse pluripotent and differentiated tissues
ChIP-on-chip analysis using a methylation specific antibody was performed on a series of pluripotent and differentiated tissues.
ORGANISM(S): Mus musculus 
2008-06-27 | E-TABM-476 | biostudies-arrayexpress
ProteomicsTumour-associated antigenic peptides are present in the HLA class I ligandome of cancer cell line derived extracellular vesicles.
The recent success of monoclonal antibody checkpoint inhibitor therapies that enhance the ability of CD8+ T cells to detect cancer-related antigenic peptides has refocused the need to fully understand the repertoire of peptides being presented to the immune system. Whilst the peptide ligandome prese...
ORGANISM(S): Homo sapiens (Human) 
2022-04-01 | PXD025345 | Pride
Cancer Extracellular vesicles T-cell epitopes Taa Hla class i ligandome Evs Tumour. Tumour-associated antigens 
TranscriptomicsChromatin immunoprecipitation of mouse erythroid tissue with RNAPII-S5P ChIP e4C to identify spatial interactomes of mouse globin genes, using alpha and beta globin genes as baits
RNAPII-S5P ChIP e4C was performed on mouse erythroid tissue, using the alpha and beta globin genes as baits
ORGANISM(S): Mus musculus 
2009-12-01 | E-TABM-822 | biostudies-arrayexpress
TranscriptomicsCharacterising the cellular activity of new Fibroblast Growth Factor Receptor tyrosine kinase inhibitors and identification of a gatekeeper mutation in FGFR3 as a mechanism of acquired resistance.
Fibroblast growth factor receptors (FGFRs) can act as driving oncoproteins in certain cancers due to mutation, over-expression or activating gene fusions and are therefore attractive drug targets. Here we have characterized tumour cell responses to three new inhibitors of FGFR1-3, AZ12576089, AZ129...
ORGANISM(S): Homo sapiens 
2012-10-02 | E-TABM-1222 | biostudies-arrayexpress
GenomicsSingle-Cell Whole-Genome Bisulfite Sequencing for Analysis of Epigenetic Heterogeneity
We report a single-cell whole-genome bisulfite sequencing method (scBS-Seq) capable of accurately measuring DNA methylation at up to 36% of CpGs. We observed that ESCs grown in serum/LIF or 2i/LIF both display epigenetic heterogeneity, with M-bM-^@M-^\2i-likeM-bM-^@M-^] cells present in serum cultur...
ORGANISM(S): Mus musculus 
2014-07-18 | E-GEOD-56879 | biostudies-arrayexpress
UnknownStructural Snapshots for Mechanism-Based Inactivation of a Glycoside Hydrolase by Cyclopropyl Carbasugars.
Not available
S-EPMC5132143 | biostudies-literature
UnknownRevealing the mechanism for covalent inhibition of glycoside hydrolases by carbasugars at an atomic level.
Not available
S-EPMC6089974 | biostudies-literature
UnknownStructural basis for a class of nanomolar influenza A neuraminidase inhibitors.
Not available
S-EPMC3797432 | biostudies-literature
UnknownDating Ammonia-Oxidizing Bacteria with Abundant Eukaryotic Fossils.
Not available
S-EPMC11135946 | biostudies-literature
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