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GenomicsAnp32e is a histone chaperone that removes H2A.Z from chromatin
We report a genome wide enrichment, redistribution and accumulation of H2A.Z at specific chromatin control regions, in particular at enhancers and insulators, in mouse embryonic fibroblasts depleted for Anp32e (MEFs Anp32e-/-). H2A.Z ChIP-seq in MEFs WT (+/+) or KO (-/-) for Anp32e.
ORGANISM(S): Mus musculus 
2014-01-22 | E-GEOD-51579 | biostudies-arrayexpress
ProteomicsANP32e binds histone H2A.Z in a cell cycle-dependent manner and regulates its protein stability in the cytoplasm
ANP32e, a chaperone of H2A.Z, is receiving increasing attention because of its link to cancer growth and progression. An unanswered question is whether ANP32e regulates H2A.Z dynamics during the cell cycle; if so, this could have clear implications for the proliferation of cancer cells. Using the hu...
ORGANISM(S): Homo sapiens (Human) 
2024-05-23 | PXD033229 | Pride
Protein stability Epigenetics Chromatin remodeling Anp32e Chaperone H2a.z Cell cycle Chromatin 
UnknownANP32E contributes to gastric cancer progression via NUF2 upregulation.
Not available
S-EPMC9364136 | biostudies-literature
ProteomicsLockd promotes myoblast proliferation and skeletal muscle regeneration through binding with DHX36 to facilitate unwinding of 5’UTR rG4 and translation of Anp32e mRNA
Adult muscle stem cells, also known as satellite cells (SCs) play pivotal roles in injury induced muscle regeneration and our knowledge of long non-coding RNA (lncRNA) functions in SCs remains limited. Here we identify a lncRNA, Lockd which is induced in activated SCs upon acute muscle injury. We de...
ORGANISM(S): Mus Musculus 
2022-05-24 | PXD033658 |
GenomicsGenome-wide Chromatin Accessibility is Restricted by ANP32E [ATAC-seq]
Genome-wide Chromatin Accessibility is Restricted by ANP32E [ATAC-seq]
PRJNA608062 | ENA
GenomicsGenome-wide Chromatin Accessibility is Restricted by ANP32E [CUT&Tag]
Genome-wide Chromatin Accessibility is Restricted by ANP32E [CUT&Tag]
PRJNA650548 | ENA
UnknownGenome-wide chromatin accessibility is restricted by ANP32E.
Not available
S-EPMC7546623 | biostudies-literature
UnknownAnp32e, a higher eukaryotic histone chaperone directs preferential recognition for H2A.Z.
Not available
S-EPMC3975505 | biostudies-literature
UnknownANP32E induces tumorigenesis of triple-negative breast cancer cells by upregulating E2F1.
Not available
S-EPMC5983205 | biostudies-literature
GenomicsSubtype-Independent ANP32E Reduction During Breast Cancer Progression in Accordance with Chromatin Relaxation.
Subtype-Independent ANP32E Reduction During Breast Cancer Progression in Accordance with Chromatin Relaxation.
PRJNA780871 | ENA
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