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ProteomicsMass Spectrometry analysis of human matched Anterior and Posterior lobes of Pituitary
This study provides a comprehensive proteomic analysis of five matched pairs of the anterior and posterior lobe of the pituitary, which was used to study the proteomic signature specific to both anterior and posterior lobes. Anterior Lobe n=5 Posterior Lobe n=5 A441 PT441 A442 ...
ORGANISM(S): Homo sapiens (Human) 
2022-12-07 | PXD030235 | Pride
Pituitary Label free quantification lfq Proteomics Obribtrap based mass spectrometery analysis Lc-msms 
ProteomicsProteomic Blueprint of the Pituitary anterior and posterior lobes for better understanding of the physiology of pituitary gland.
This study provides a comprehensive proteomic analysis of five matched pairs of the anterior and posterior lobe of the pituitary, which was used to study the proteomic signature specific to both anterior and posterior lobes.
ORGANISM(S): Homo Sapiens 
2022-12-06 | PXD029991 | panorama
TranscriptomicsTranscription profiling of rat anterior pituitary gland response to diethylstilbestrol
This SuperSeries is composed of the following subset Series:; GSE4028: Effects of diethylstilbestrol (DES) on the anterior pituitary gland of the ACI, Copenhagen and Brown Norway Rat. GSE4080: Effect of DES-treated Ept congenic rat lines on gene expression in the anterior pituitary gland. GSE4081: E...
ORGANISM(S): Rattus norvegicus 
2008-06-12 | E-GEOD-4083 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of rat anterior pituitary gland using DES-treated COPxACI F2 rats - Expression QTL mapping.
Anterior pituitary glands were isolated from 21 week old male rats treated for 12 weeks with the synthetic estrogen diethylstilbestrol (DES). 43 COPxACI F2 animals were selected based on pituitary weight phenotypic extremes: 22 highest and 21 lowest pituitary weights in our F2 population. Expression...
ORGANISM(S): Rattus norvegicus 
2008-06-12 | E-GEOD-4081 | biostudies-arrayexpress
TranscriptomicsSingle-cell transcriptomics of neonatal mouse anterior pituitary in steady-state conditions and after transgenically inflicted local damage
The mouse pituitary gland undergoes vivid maturation immediately after birth. During this process, the local stem cell compartment shows signs of activation including elevated abundance and expression of stemness pathways when compared to adult pituitary stem cells. In addition, we found that the ne...
ORGANISM(S): Mus musculus 
2022-07-11 | E-MTAB-11337 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of rat ept congenic lines anterior pituitary gland after DES treatment
Anterior pituitary glands were isolated from 21 week old male rats treated for 12 weeks with the synthetic estrogen diethylstilbestrol (DES). Three biological replicates were prepared for each of 4 congenic lines: Ept1, Ept2, Ept6, and Ept9. Congenic rat lines were constructed by introgressing COP a...
ORGANISM(S): Rattus norvegicus 
2008-06-12 | E-GEOD-4080 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of rat anterior pituitary gland of the ACI treated with diethylstilbestrol (DES) from Copenhagen and Brown Norway strains.
Anterior pituitary glands were isolated from 21 week old male rats either untreated or treated for 12 weeks with the synthetic estrogen diethylstilbestrol (DES). Three biological replicates were prepared for untreated, control animals and four biological replicates were prepared for DES-treated anim...
ORGANISM(S): Rattus norvegicus 
2009-01-09 | E-GEOD-4028 | biostudies-arrayexpress
TranscriptomicsComparative anterior pituitary miRNA and mRNA expression profiles of Bama minipigs and Landrace pigs reveal potential molecular network involved in animal postnatal growth [mRNA-Seq]
The anterior pituitary is the most important endocrine organ modulating animal postnatal growth, mainly by controlling growth hormone (GH) gene transcription, synthesis, and secretion. As an ideal model for animal postnatal growth studies, the Bama minipig is characterized as having a lower growth p...
ORGANISM(S): Sus scrofa 
2015-05-05 | E-GEOD-68490 | biostudies-arrayexpress
TranscriptomicsComparative anterior pituitary miRNA and mRNA expression profiles of Bama minipigs and Landrace pigs reveal potential molecular network involved in animal postnatal growth [miRNA array]
The anterior pituitary is the most important endocrine organ modulating animal postnatal growth, mainly by controlling growth hormone (GH) gene transcription, synthesis, and secretion. As an ideal model for animal postnatal growth studies, the Bama minipig is characterized as having a lower growth p...
ORGANISM(S): Sus scrofa 
2015-05-05 | E-GEOD-68489 | biostudies-arrayexpress
ProteomicsProteomic profiling of anterior pituitary of heifer calves offered either a high or moderate plane of nutrition in early life
Enhanced nutrition during the early calfhood period has been shown to hasten the onset of puberty in heifer calves. The hypothalamic-pituitary-ovarian biochemical signalling axis regulates reproductive development in heifers, with the dynamics of gonadotropin pulsatility within the anterior pituitar...
ORGANISM(S): Bos taurus (Bovine) 
2024-07-04 | PXD042011 | Pride
Anterior pituitary Diet Heifer calves 
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