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ProteomicsAntibodies to protozoan variable surface antigens induce antigenic variation
The genomes of most protozoa encode families of variant surface antigens, whose mutually exclusive changes in expression allow parasitic microorganisms to evade the host immune response1. It is widely assumed that antigenic variation in protozoan parasites is accomplished by the spontaneous appearan...
ORGANISM(S): Giardia lamblia ATCC 50803 
2023-05-10 | PXD031141 | Pride
Exosomes Microvesicles Giardia Antigenic variation 
ProteomicsThe Trypanosoma cruzi Antigen and Epitope Atlas: fine characterization of antibody specificities in human Chagas Disease patients across human populations
These assays represent antibody-binding assays to analyze seroprevalence of antigens and epitopes at the individual level and also to perform fine epitope mapping characterizations. In this screening 392,299 peptides derived from reactive (antigenic) regions of Trypanosoma cruzi proteins were displa...
ORGANISM(S): Homo sapiens 
2022-08-20 | E-MTAB-11655 | biostudies-arrayexpress
TranscriptomicsP. falciparum Heterochromatin Protein 1 Marks Genomic Loci Linked to Phenotypic Variation of Exported Virulence Factors
Epigenetic processes are the main conductors of phenotypic variation in eukaryotes. The malaria parasite Plasmodium falciparum employs antigenic variation of the major surface antigen PfEMP1, encoded by 60 var genes, to evade acquired immune responses. PfEMP1 also mediates sequestration of infected ...
ORGANISM(S): Plasmodium falciparum 
2010-05-06 | E-GEOD-17029 | biostudies-arrayexpress
UnknownAntigenic determinants of alpha-like proteins of Streptococcus agalactiae.
Not available
S-EPMC524766 | biostudies-literature
ProteomicsUMSBP2 is chromatin remodeler that functions in regulation of gene expression and suppression of antigenic variation in trypanosomes
Universal Minicircle Sequence binding proteins (UMSBPs) are CCHC-type zinc-finger proteins that bind the single-stranded G-rich UMS sequence, conserved at the replication origins of minicircles in the kinetoplast DNA, the mitochondrial genome of trypanosomatids. Trypanosoma brucei UMSBP2 has been re...
ORGANISM(S): Trypanosoma brucei 
2023-07-20 | PXD030439 | Pride
Trypanosomes Antigenic variation Gene expression Umsbp Chromatin remodeling 
UnknownArVirInd-a database of arboviral antigenic proteins from the Indian subcontinent.
Not available
S-EPMC9590419 | biostudies-literature
ProteomicsIn vivo identification of Toxoplasma gondii antigenic proteins and in silico study of their polymorphism.
This study aims to identify novel candidates for the development of serotyping assays for Toxoplasma gondii (T. gondii). We employed an in vivo approach, utilizing co-immunoprecipitation (Co-IP) with sera from infected mice to identify antigenic proteins, followed by detection via LC-MS/MS. Addition...
ORGANISM(S): Toxoplasma gondii 
2026-02-09 | PXD058695 | Pride
Toxoplasma gondii Antigenic protein Lc-ms/ms 
UnknownCharacterization of antigenic proteins of the Taenia solium postoncospheral form.
Not available
S-EPMC11197303 | biostudies-literature
MetabolomicsA Combined Proteomic and Metabolomic Strategy for Allergens Characterization in Natural and Fermented Brassica napus Bee Pollen

Bee pollen is consumed for its nutritional and pharmacological benefits, but it also contains hazardous allergens which has not been identified. Here, we identified 2 potential allergens, glutaredoxin and oleosin-B2, in Brassica napus (B. napus) bee pollen using mass spectrometr...

2022-03-23 | MTBLS3950 | MetaboLights
UnknownAntibody screening reveals antigenic proteins involved in Talaromyces marneffei and human interaction.
Not available
S-EPMC10315666 | biostudies-literature
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