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Metabolomics3,4-Dihydroxybenzaldehyde exerts anti-Alzheimer's effects by inhibiting Aβ protofibril assembly and activating antioxidant defense mechanisms

Broad-spectrum metabolomic analyses reveal that DBD markedly modulates the nematode’s metabolic profile. DBD enhances the activation of transcription factors DAF-16/FOXO and SKN-1/Nrf2, increasing resistance to oxidative and thermal stress. These findings suggest that DBD possesses multi-target t...

2025-12-24 | MTBLS13568 | MetaboLights
GenomicsNeofusicoccum laricinum disrupts larch defenses through coordinated cell wall degradation and antioxidant suppression
Neofusicoccum laricinum disrupts larch defenses through coordinated cell wall degradation and antioxidant suppression
PRJNA1414440 | ENA
GenomicsReduced cardiac antioxidant defenses mediate increased susceptibility to workload-induced myocardial injury in males with genetic cardiomyopathy.
Reduced cardiac antioxidant defenses mediate increased susceptibility to workload-induced myocardial injury in males with genetic cardiomyopathy.
PRJNA1051165 | ENA
UnknownAntioxidant Defenses in the Brains of Bats during Hibernation.
Not available
S-EPMC4806925 | biostudies-literature
UnknownControl of redox balance by the stringent response regulatory protein promotes antioxidant defenses of Salmonella.
Not available
S-EPMC2978607 | biostudies-literature
TranscriptomicsNeofusicoccum laricinum disrupts larch defenses through coordinated cell wall degradation and antioxidant suppression
Larch (Larix spp.), a key species in China's reforestation efforts, faces increasing threats from shoot blight caused by Neofusicoccum laricinum. This study characterized the biological traits, virulence mechanisms, and host interactions of this pathogen to inform disease management. Twenty-five N. ...
ORGANISM(S): Larix kaempferi 
2026-01-27 | GSE317540 | GEO
UnknownBarley stripe mosaic virus γb protein disrupts chloroplast antioxidant defenses to optimize viral replication.
Not available
S-EPMC8365260 | biostudies-literature
ProteomicsGlycolytic profile shift and antioxidant triggering in symbiont-free and H2O2-resistant Strigomonas culicis
During their life cycle, trypanosomatids are exposed to stress conditions and adapt their energy and antioxidant metabolism to colonize their hosts. Strigomonas culicis is a monoxenous protist found in invertebrates with an endosymbiotic bacterium that completes essential biosynthetic pathways for t...
ORGANISM(S): Strigomonas culicis 
2019-11-27 | PXD015717 | Pride
Energetic metabolism Ascorbate peroxidase Pentose phosphate pathway Antioxidant system Oxidative stress 
UnknownBixin Combined with Metformin Ameliorates Insulin Resistance and Antioxidant Defenses in Obese Mice.
Not available
S-EPMC11434661 | biostudies-literature
UnknownRedox Imbalance and Antioxidant Defenses Dysfunction: Key Contributors to Early Aging in Childhood Cancer Survivors.
Not available
S-EPMC11590913 | biostudies-literature
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