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MetabolomicsMetabolomic profiling reveals the effects of early-life lactoferrin intervention on protein synthesis, energy production and antioxidative capacity in the liver of suckling piglets

The objective of this study was to reveal the effects of early life lactoferrin intervention on the liver metabolism in the suckling piglets. Sixty newborn piglets with an average initial body weight (BW) of 1.51 ± 0.05 kg were assigned to the control (CON) group and the lactoferrin (LF) group. P...

2022-03-01 | MTBLS2279 | MetaboLights
MetabolomicsSystems toxicology of a tire-wear pollutant: Multi-omics evidence for bioenergetic reprogramming in freshwater clams

The increasing release of tire-derived transformation products into aquatic ecosystems has raised significant environmental concerns, particularly regarding 6PPD-quinone (6PPDQ), a highly toxic compound formed from a widely used tire antioxidant. Despite growing attention, its chronic effects and...

2026-03-26 | MTBLS14142 | MetaboLights
GenomicsCandida albicans Sfp1 participates in the regulation of multiple antioxidative systems
Candida albicans Sfp1 participates in the regulation of multiple antioxidative systems
PRJNA524312 | ENA
TranscriptomicsComparison of bone marrow-derived macrophages from BALB/c and C57BL/6 mice with and without interferon-gamma stimulation.
ABSTRACT Macrophages are essential components of the innate immune system and crucial for pathogen elimination in early stages of infection. We previously observed that bone marrow-derived macrophages (BMM) from C57BL/6 mice exhibited increased killing activity against Burkholderia pseudomallei comp...
ORGANISM(S): Mus musculus 
2014-04-15 | E-GEOD-39349 | biostudies-arrayexpress
TranscriptomicsNovel antioxidative peptides with potential to reduce psoriatic changes in PBMCs
Oxidative damage contributes significantly to the pathogenesis of psoriasis. We recently developed antioxidative peptides (UPF peptides) activating the endogenous glutathione system (GSH). In the present study, we analyzed gene expression profiles in the samples of psoriasis patients to find if thes...
ORGANISM(S): Homo sapiens 
2012-08-22 | E-GEOD-40263 | biostudies-arrayexpress
ProteomicsAlkylation Damage by Lipid Electrophiles Targets Functional Protein Systems
These data correspond to "Alkylation Damage by Lipid Electrophiles Targets Functional Protein Systems," a paper from Codreanu, Liebler, et al, published at the journal _Molecular and Cellular Proteomics_ in 2013. Modifications also include: 4-hydroxynonenal (HNE) (UniMod #53), H(16) C(9) O(2), Mono...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2013-11-18 | MSV000078490 | MassIVE
UnknownThe Effect of Thiamine Concentration on the Antioxidative Activity Indices in Tea Extracts.
Not available
S-EPMC6912681 | biostudies-literature
TranscriptomicsCoordination of frontline defense mechanisms under severe oxidative stress.
Oxidative stress (OS) results from genetic defects or stressful environmental challenges that cause unchecked production of reactive oxygen species (ROS). OS has been implicated in many diseases due to its wide ranging damage to nucleic acids, proteins and lipids. Using Halobacterium salinarum NRC...
ORGANISM(S): Halobacterium salinarum 
2010-05-26 | E-GEOD-17515 | biostudies-arrayexpress
UnknownImmunomodulatory and Antioxidative potentials of adipose-derived Mesenchymal stem cells isolated from breast versus abdominal tissue: a comparative study.
Not available
S-EPMC7536259 | biostudies-literature
TranscriptomicsMitochondrial two-component signaling systems in Candida albicans
Two-component signal transduction pathways are one of the primary means by which microorganisms respond to environmental signals. These signaling cascades originated in prokaryotes and were inherited by eukaryotes via endosymbiotic lateral gene transfer from ancestral cyanobacteria. We report here t...
ORGANISM(S): Candida albicans 
2013-07-02 | E-GEOD-45438 | biostudies-arrayexpress
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