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TranscriptomicsActivation of ER-alpha network in MMTV-Wnt/ILK mammary tumors
A transgenic mouse model, MMTV-Wnt/ILK, with mammary specific expression of both Wnt-1 and ILK, was generated by crossing the two mouse lines MMTV-Wnt-1 and MMTV-ILK. Affymetrix Mouse Exon chips were hybridized with material from four independent mammary tumors from each MMTV-Wnt-1 and MMTV-Wnt/ILK ...
ORGANISM(S): Mus musculus 
2010-07-08 | E-GEOD-19300 | biostudies-arrayexpress
UnknownLinking the region-specific tissue microstructure to the biaxial mechanical properties of the porcine left anterior descending artery.
Not available
S-EPMC10230544 | biostudies-literature
TranscriptomicsTranscript Analysis of Human Mammary Cell Subsets using SAGE
Highly purified subpopulations of primitive bipotent and committed luminal progenitor cells as well as mature luminal and myoepithelial cells from normal human mammary tissue were isolated and compared their transcriptomes which were obtained using PCR-Long-SAGE technology. Keywords: mammary progeni...
ORGANISM(S): Homo sapiens 
2008-05-09 | E-GEOD-11387 | biostudies-arrayexpress
TranscriptomicsTestosterone-dependent and independent transcriptional networks in the hypothalamus of Gpr54 and Kiss1 knockout male mice
Humans and mice with loss of function mutations in GPR54 (KISS1R) or kisspeptin (KISS1) do not progress through puberty, caused by a failure to release GnRH. The transcriptional networks regulated by these proteins in the hypothalamus have yet to be explored by genome-wide methods. Using micro-disse...
ORGANISM(S): Mus musculus 
2011-08-21 | E-GEOD-28383 | biostudies-arrayexpress
GenomicsMETABRIC
The elucidation of breast cancer subgroups and their molecular drivers requires integrated views of the genome and transcriptome from representative numbers of patients. We present an integrated analysis of copy number and gene expression in a discovery and validation set of 997 and 995 primary brea...
EGAS00000000083 | EGA
GenomicsHMM Segmented CNA (discovery set) - samples
Segmented (HMM) copy number aberrations (CNA); discovery set
EGAD00010000217 | EGA
GenomicsCBS Segmented CNV (discovery set) - samples
Segmented (CBS) copy number variants (CNV); discovery set
EGAD00010000214 | EGA
GenomicsNormalized expression (discovery set) - samples
Normalized expression data; discovery set
EGAD00010000210 | EGA
GenomicsIllumina_HT12_raw - samples
Illumina HT 12 IDAT files
EGAD00010000436 | EGA
GenomicsCBS Segmented CNA (validation set) - samples
Segmented (CBS) copy number aberrations (CNA); validation set
EGAD00010000215 | EGA
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