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UnknownOxa-376 and Oxa-530 variants of β-lactamase: computational study uncovers potential therapeutic targets of Acinetobacter baumannii.
Not available
S-EPMC9412156 | biostudies-literature
TranscriptomicsTranscription profiling by array of human peripheral blood mononuclear cells from patients with peripheral arterial disease
Peripheral arterial disease (PAD) is a relatively common manifestation of systemic atherosclerosis that leads to progressive narrowing of the lumen of leg arteries. Circulating monocytes are in contact with the arterial wall and can serve as reporters of vascular pathology in the setting of PAD. We ...
ORGANISM(S): Homo sapiens 
2012-03-22 | E-GEOD-27034 | biostudies-arrayexpress
UnknownStructure Activity Relationship Studies around DB18, a Potent and Selective Inhibitor of CLK Kinases.
Not available
S-EPMC9571063 | biostudies-literature
ProteomicsGlobal and comparative proteome signatures in the lens capsule, trabecular meshwork, and iris of patients with pseudoexfoliation glaucoma
Pseudoexfoliation (PXF) is characterized by the accumulation of exfoliative material in the eye and high rates of blindness, if left untreated. Pseudoexfoliation glaucoma (PXG) is generally diagnosed too late due to its asymptomatic nature, necessitating the development of new effective screening to...
ORGANISM(S): Homo sapiens (Human) 
2022-05-20 | PXD032202 | Pride
Mass spectroscopy Pseudoexfoliation glaucoma (pxg) Lens capsule Lysyl oxidase Iris Trabecular meshwork Pseudoexfoliation (pxf) Extracellular matrix 
GenomicsIdentification of gene mutations and fusion genes in patients with Sézary Syndrome
Sezary syndrome (SS) is a leukemic form of cutaneous T-cell lymphoma (CTCL) with an aggressive clinical course. The goal of our study is to understand the genetic basis of the disease by looking for driver gene mutations and fusion genes in 15 erythrodermic patients with circulating Sezary cels, fou...
EGAS00001001706 | EGA
TranscriptomicsMultidrug Resistance-Linked Gene Signature Predicts Overall Survival of Patients with Primary Ovarian Serous Carcinoma
This study assesses the ability of multidrug resistance (MDR)-associated gene expression patterns to predict survival in patients with newly diagnosed carcinoma of the ovary. The scope of this research differs substantially from that of previous reports, as a very large set of genes was evaluated wh...
ORGANISM(S): Homo sapiens 
2012-04-19 | E-GEOD-30009 | biostudies-arrayexpress
TranscriptomicsTemporal Expression Profiling Identifies Pathways Mediating Effect of Causal Variant on Phenotype
Temporal expression profiling during sporulation for MKT1 allele replacement strains in S288c
ORGANISM(S): Saccharomyces cerevisiae 
2015-04-18 | E-MTAB-3454 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of Campylobacter jejuni flagellar mutants to investigate the RpoN and FliA regulons, and the flagellar hook length control gene fliK
Data is also available from http://bugs.sgul.ac.uk/E-BUGS-50
ORGANISM(S): Campylobacter jejuni 
2007-09-06 | E-BUGS-50 | biostudies-arrayexpress
TranscriptomicsBulk RNA-seq of untreated human cell lines from multiple tissues
Bulk RNA-seq profiling of untreated human cell lines derived from blood, breast and bladder tissues (MCF7, MDA-MB-231, KMCB2, Jurkat) to characterise baseline transcriptional differences across cellular contexts.
ORGANISM(S): Homo sapiens 
2026-01-25 | E-MTAB-16514 | biostudies-arrayexpress
TranscriptomicsHuman and mouse DRIP-seq and DRIPc-seq
This study profiles RNA:DNA hybrid formation in human and mouse cell lines. DRIPc-seq (strand-specific R-loop mapping) was performed on human NT2 cells and mouse 3T3 cells. DRIP-seq (R-loop mapping) was performed on human NT2 and K562 and mouse E14 and 3T3 cell lines. MethylC-seq and RNA-seq were pe...
ORGANISM(S): Homo sapiens 
2016-06-30 | E-GEOD-70189 | biostudies-arrayexpress
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