Iris - OmicsDI

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Unknown (2047)
Transcriptomics (426)
Genomics (397)
Proteomics (166)
Metabolomics (65)
Clinical (25)
Other (5)
Models (2)
Multiomics (1)

Organisms

Homo sapiens (475)
Mus musculus (121)
Allexis (65)
Arabidopsis thaliana (27)
Danio rerio (8)
Escherichia coli (5)
Saccharomyces cerevisiae (3)
Rattus norvegicus (3)
Drosophila melanogaster (3)
Pimephales promelas (2)
Gallus gallus (2)
Bacillus thuringiensis serovar thuringiensis (2)
Lactococcus lactis (1)
Lactobacillus johnsonii (1)
Leishmania major (1)
Listeria monocytogenes EGD-e (1)
Bacillus subtilis (1)
Cryptococcus neoformans (1)
Iris tectorum (1)
Notophthalmus viridescens (1)
Iris atropurpurea (1)
Pleurodeles waltl (1)
Macaca mulatta (1)
Sus scrofa (1)
Chlamydomonas reinhardtii (1)
Medicago truncatula (1)
Neurospora crassa (1)
Oryza sativa (1)
Taraxacum (1)
Pseudomonas aeruginosa (1)

Organisms

Homo sapiens (41)
Mus musculus (20)
Iris macrosiphon (6)
Iris germanica (5)
Iris foetidissima (5)
Iris domestica (5)
Cynoscion nebulosus (4)
Iris japonica (4)
Apatura iris (3)
rhizosphere metagenome (3)
Iris atropurpurea (2)
Iris tectorum (2)
Iris fulva (2)
Haliotis iris (2)
Iris (2)
Iris cangshanensis (2)
Iris dichotoma (2)
Lepidothrix iris (1)
Lamprotornis iris (1)
Iris pallida (1)
Iris bulleyana (1)
1649849 (1)
Iris virginica (1)
Iris sibirica (1)
Coeligena iris (1)
Iris lactea var. chinensis (1)
Iris speculatrix (1)
Iris lactea (1)
Iris hippolyti (1)
Iris lactea var. lactea (1)

Repository

biostudies-arrayexpress (401)
ENA (211)
EGA (157)
pride (65)
geo (56)
GNPS (52)
MassIVE (49)
jPOST (44)
MetaboLights (13)
iProX (5)
EVA (3)
BioModels (2)
ExpressionAtlas (1)
GPMDB (1)
PAXDB (1)

Tissue

Cell culture (15)
Leaf (8)
Epithelial cell (7)
Iris (7)
Eye (4)
Retina (4)
Blood cell (3)
Blood plasma (3)
Permanent cell line cell (3)
Choroid (2)
Conjunctiva (2)
Cornea (2)
Plant cell (2)
Sclera (2)
Seed (2)
Tear (2)
Vitreous humor (2)
Anterior chamber of the eye (1)
Astrocyte (1)
Blood (1)
Brain (1)
Cell suspension culture (1)
Choroidal cell of the eye (1)
Ciliary body (1)
Endothelial cell of umbilical vein (1)
Eye trabecular meshwork (1)
Flower (1)
Heart (1)
JURKAT cell (1)
T cell (1)

Disease

Colorectal cancer (4)
Colorectal Neoplasms (4)
Normal (3)
Breast cancer (3)
Metastatic colorectal cancer (3)
Disease free (3)
Mammary tumor (2)
Unresectable Colorectal Cancer (2)
Metastatic colorectal cancer (2)
Colorectal cancer (2)
Acute leukemia (2)
Sporadic basal-like breast cancer (1)
Liver cancer (1)
MFC II (1)
Ductal breast cancer (1)
HIV-Tuberculosis with Immune Reconstitution Inflammatory Syndrome (1)
Tumour (1)
Cancer (1)
Invasive ductal carcinoma (1)
KRAS wild type metastatic colorectal cancer (1)
Unresectable or recurrent colorectal cancer (1)
Colonrectal cancer (1)
Advanced/metastatic colorectal cancer (1)
1st line or 2nd line therapy for unresectable colorectal cancer (1)
Metastatic Colorectal Cancer (1)
Patients with advanced or recurrent colorectal cancer after failure or unfeasible L-OHP+5-FU regimen (1)
Colorectal Cancer (1)
Not Available (1)
Brain glioblastoma multiforme (1)
COVID-19 (1)

Technology Type

Mass Spectrometry (65)
Shotgun proteomics (36)
Affinity purification coupled with mass spectrometry proteomics (10)
Bottom-up proteomics (10)
Mass spectrometry (7)
Data-independent acquisition (5)
Mass spectrometry assay (4)
Gel-based experiment (4)
ILLUMINA, Illumina HiSeq 2500 (2)
Illumina Genome Analyzer II, Illumina HiSeq 2000 (2)
NMR spectroscopy (2)
All-ion fragmentation (2)
MSE (2)
Illumina MiSeq, Illumina HiSeq 2500, ILLUMINA (1)
Illumina HumanOmni5 (1)
Illumina HiSeq 2500, ILLUMINA (1)
ILLUMINA, Illumina HiSeq 2500, Illumina HiSeq 2000 (1)
Illumina HumanOmni2.5, Illumina HiSeq 2000 (1)
AB SOLiD 4 System (1)
Illumina HumanExome-12v1_A-GenCall, zCall, GenoSNP, - Illuminus (1)
Illumina HiSeq 2000 (1)
Affinity proteomics (1)
Data-dependent acquisition (1)
DiaPASEF (1)
HDMSE (1)
SWATH MS (1)
Top-down proteomics (1)

Instrument Platform

LTQ Orbitrap Velos (36)
Q Exactive (14)
GC-MS (12)
Illumina NovaSeq 6000 (10)
GC MS (10)
Q Exactive Plus (9)
Illumina HiSeq 4000 (7)
Illumina HiSeq 2500 (5)
NextSeq 500 (5)
Illumina HiSeq 2000 (4)
ACQUITY UPLC I-Class (4)
- (3)
454 GS FLX+ (2)
Illumina MiSeq (2)
Illumina HiSeq 1500 (2)
Affymetrix Array scanner (1)
Affymetrix hybridization station (1)
GenePix 4000B Microarray Scanner (Molecular Devices). (1)
AgilentM-^Rs Microarray Hybridization Oven (1)
Affymetrix GeneChip Scanner 3000 7G (1)
AB SOLiD 4 System (1)
The Agilent scanner G2565BA (1)
NanoDrop ND-1000 Spectrophotometer (NanoDrop Technologies) (1)
Illumina Genome Analyzer IIx (1)
Illumina NovaSeq X (1)
Nanodrop (1)
None (1)
NA (1)
Illumina MiniSeq (1)
BGISEQ-500 (1)

Publication Date

2013 (69)
2016 (53)
2014 (50)
2012 (49)
2024 (48)
2015 (47)
2011 (41)
2010 (40)
2022 (34)
2017 (33)
2021 (31)
2023 (30)
2025 (28)
2018 (25)
2026 (23)
2019 (19)
2008 (18)
2020 (17)
2009 (15)
2007 (11)
2005 (5)
2006 (4)

UNIPROT ID/AC

P42263 (1)
Q13002 (1)
14331_ORYSJ (1)
14332_ORYSJ (1)
14333_ORYSJ (1)
14334_ORYSJ (1)
14335_ORYSJ (1)
14336_ORYSJ (1)
2ABA_ORYSJ (1)
40C1_ORYSJ (1)
40G2_ORYSJ (1)
40G3_ORYSJ (1)
4CL3_ORYSJ (1)
4CL4_ORYSJ (1)
4CLL1_ORYSJ (1)
4CLL4_ORYSJ (1)
4CLL5_ORYSJ (1)
6PGD1_ORYSJ (1)
6PGD2_ORYSJ (1)
6PGL2_ORYSJ (1)
6PGL3_ORYSJ (1)
6PGL4_ORYSJ (1)
A0A024FLK4_ORYSJ (1)
A0A0N7KC78_ORYSJ (1)
A0A0N7KD71_ORYSJ (1)
A0A0N7KDZ0_ORYSJ (1)
A0A0N7KE18_ORYSJ (1)
A0A0N7KE80_ORYSJ (1)
A0A0N7KEH6_ORYSJ (1)
A0A0N7KET0_ORYSJ (1)

CHEBI ID

CHEBI:16737 (5)
CHEBI:18237 (4)
CHEBI:16761 (4)
CHEBI:68567 (4)
CHEBI:25094 (4)
CHEBI:18186 (4)
CHEBI:24898 (4)
CHEBI:28044 (4)
CHEBI:29016 (4)
CHEBI:17596 (4)
CHEBI:30769 (4)
CHEBI:65004 (3)
CHEBI:33277 (3)
CHEBI:15379 (1)
CHEBI:16812 (1)
CHEBI:16982 (1)
CHEBI:15688 (1)
CHEBI:16444 (1)
CHEBI:30089 (1)
CHEBI:15350 (1)
CHEBI:15351 (1)
CHEBI:15346 (1)
CHEBI:24996 (1)
CHEBI:18367 (1)
CHEBI:16236 (1)
CHEBI:15343 (1)
CHEBI:15361 (1)
CHEBI:15422 (1)
CHEBI:16908 (1)
CHEBI:15846 (1)

Metabolite Name

N1-Methyl-2-pyridone-5-carboxamide (3)
Leucine (3)
Choline (3)
Creatinine (3)
Creatine (3)
ADP (3)
Pantothenic acid (3)
Xanthosine (3)
Traumatic acid (3)
Phenylalanine (3)
Isoleucine (3)
Secoisolariciresinol (2)
6''-O-Acetylgenistin (2)
Dimethylmalonic acid (2)
N-Acetylimidazole (2)
Vanilpyruvic acid (2)
Dihydrofukinolide (2)
MG(0:0/16:1(9Z)/0:0) (2)
Urolithin B (2)
Deoxycorticosterone (2)
5,6-Dihydro-11-methoxyyangonin (2)
Cucurbic acid (2)
Coniferin (2)
(1xi,3xi)-1,2,3,4-Tetrahydro-1-methyl-beta-carboline-3-carboxylic acid (2)
Tetrahydro-2,5-furan-diacetic acid (2)
Indan-1-ol (2)
Sulcatone (2)
Monoisobutyl phthalic acid (2)
LysoPE(0:0/16:0) (2)
Adenosine diphosphate ribose (2)

First Public Date

2024 (46)
2025 (28)
2023 (25)
2022 (22)
2021 (21)
2026 (17)
2014 (16)
2020 (10)
2019 (10)
2018 (7)
2017 (4)
2013 (3)
2016 (1)
2015 (1)

Modelling Approach

Ordinary differential equation model (2)

Study status

Completed (13)
Recruiting (6)
Not provided (3)
Suspended (1)
Active, not recruiting (1)
Not yet recruiting (1)

Lab affiliation

Plant Physiology Group Westfälische WIlhelms-Universität Münster Germany (3)
McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205 USA (2)
University of Houston, Houston, TX 77204 (2)
Yale Cancer Biology Institute (2)
1Department of Ophthalmology, Johns Hopkins University School of Medicine, Baltimore, MD (1)
Aalborg University (1)
Assistant Professor (PI,ANRF-SERB project), Department of Botany, Ravenshaw University, Cuttack, Odisha- 753003 India (1)
Biomedical Research Center, University Hospital Hradec Kralove, Czech Republic (1)
Cellular Proteomics Group Helmholtz Centre for Infection Research Inhoffenstr. 7 38124 Braunschweig Germany (1)
Centro Nacional de Investigación Disciplinaria en Fisiología y Mejoramiento Animal (1)
Department of Applied Biological Science, Faculty of Science and Technology, Tokyo University of Science, Chiba, Japan. (1)
Department of Biology Wanek School of Natural Sciences High Point University 1 N University Pkwy High Point, NC 27368 USA (1)
Department of Cell Biology Harvard Medical School Boston, MA USA (1)
Department of Chemistry, Biochemistry and Pharmaceutical Sciences, University of Bern, Switzerland. (1)
Department of Ecology and Evolution, University of Lausanne, CH-1015 Lausanne, Switzerland (1)
Department of Genome Integrity, Institute of Molecular Genetics of the Czech Academy of Sciences, Prague, Czech Republic (1)
Department of Hematology, Oncology, Hemostaseology and Stem Cell Transplantation, RWTH Aachen University Medical School, Aachen, Germany, (1)
Department of Infectious Diseases, Immunology and Sexual Health and Department of Medicine, St George Hospital, University of New South Wales, 2 South Street, Kogarah, Sydney, NSW 2217, Australia (1)
Department of Molecular Genetics Faculty of Biochemistry Weizmann Institute of Science Rehovot, Israel (1)
Department of Ophthalmology, Johns Hopkins University School of Medicine (1)
Division of Pediatric Hematology and Oncology, Department of Pediatrics, The Pennsylvania State University College of Medicine (1)
Drug Discovery Biology Theme Monash Institute of Pharmaceutical Sciences Monash University 399 Royal Parade (Mail address: 381 Royal Parade) Parkville VIC 3052 Australia (1)
Duke Univeristy, Departments of Ophthalmology & Pathology (1)
Germany，Medizinische Fakultät Mannheim der Universität Heidelberg Medizin/Abteilung für vaskuläre Dysfunktion (1)
Group Leader, Proteomics of Cellular Signaling, Luxembourg Institute of Health (1)
Head of the Curie Institute Mass Spectrometry Platform (1)
Host-Parasite Interaction Bernhard Nocht Institute for Tropical Medicine Bernhard-Nocht-Str. 74 20359 Hamburg Germany (1)
Institute of Biochemistry II, Goethe University Frankfurt, Germany (1)
Institute of Molecular Biology (IMB), Mainz, Germany (1)
Institute of Molecular Biology, Ackermannweg 4, 55128 Mainz (1)

Keyword

Irinotecan (4)
S-1 (2)
L-leucovorin (1)
Irinotecan, S-1, Phase II, colorectal cancer, (1)
Phase III (1)
Leucovorin (1)
Bevacizumab (1)
Fluorouracil (1)
Oxaliplatin (1)

IsPrivate

False (2)

Study type

Transcription profiling by array (249)
Comparative genomic hybridization by array (38)
RNA-seq of coding RNA (35)
Interventional (24)
Methylation profiling by array (17)
ChIP-seq (10)
Genotyping by array (8)
Unknown experiment type (7)
DNA-seq (7)
RNA-seq of coding RNA from single cells (6)
ChIP-chip by tiling array (4)
RNAi profiling by array (2)
Other (2)
MicroRNA profiling by array (2)
Proteomic profiling by array (2)
Methylation profiling by high throughput sequencing (2)
RNA-seq of non coding RNA (2)
Human - High-throughput sequencing (1)
Plant - High-throughput sequencing (1)
Cell line - One-color microarray (1)
Transcription profiling by tiling array (1)
ChIP-chip by array (1)
ATAC-seq (1)
RIP-seq (1)
Genotyping by high throughput sequencing (1)
Observational (1)

Release Date

2021 (244)
2023 (234)
2025 (227)
2022 (215)
2020 (197)
2024 (193)
2018 (134)
2019 (124)
2016 (112)
2017 (107)
2014 (105)
2015 (102)
2013 (101)
2012 (79)
2011 (62)
2010 (61)
2026 (37)
2008 (28)
2009 (27)
2007 (20)
2006 (12)
2005 (9)
2004 (3)
2002 (3)
2000 (3)
1998 (3)
2003 (2)
2001 (1)
1999 (1)
1996 (1)

Location

Japan (23)

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The proteome of human iris

The iris is a fine structure that controls the amount of light that enters the eye. Iris diseases that result in visual disability and blindness include iritis, primary angle closure glaucoma, and pigment dispersion syndrome. A detailed investigation of the proteome of the normal human iris may prov...

ORGANISM(S): Homo Sapiens (ncbitaxon:9606)

2017-11-29 | MSV000081765 | MassIVE

The proteome of human iris - Defining the proteome of human iris, ciliary body, retinal pigment epithelium, and choroid

ORGANISM(S): Homo sapiens (Human)

2016-07-18 | PXD001424 | Pride

Microarray analysis of iris gene expression in mice with mutations relevant to glaucoma

Several ocular diseases involve the iris, notably including oculocutaneous albinism, pigment dispersion syndrome, and exfoliation syndrome. To screen for candidate genes that may be active in these diseases, genome-wide iris gene expression patterns were comparatively analyzed from mouse models of t...

ORGANISM(S): Mus musculus

2010-07-30 | E-GEOD-16994 | biostudies-arrayexpress

Primary angle closure glaucoma is characterized by altered extracellular matrix homeostasis in the iris

Purpose. To characterize the proteome of the iris in primary angle closure glaucoma (PACG). Experimental Design. In this cross-sectional study, iris samples were obtained from surgical iridectomy of 48 adults with PACG and five normal controls. Peptides from iris were analyzed using liquid chromatog...

ORGANISM(S): Homo sapiens (Human)

2022-03-01 | PXD022292 | Pride

Eye Proteomics Primary angle closure glaucoma Iris Extracellular matrix

The proteome of normal human iris, ciliary body, retinal pigment epithelium, and choroid

The iris is a fine structure that controls the amount of light that enters the eye. The ciliary body controls the shape of the lens and produces aqueous humor. The retinal pigment epithelium and choroid (RPE/choroid) are essential in supporting the retina and absorbing light energy that enters the e...

ORGANISM(S): Homo Sapiens (ncbitaxon:9606)

2017-11-29 | MSV000081766 | MassIVE

A proteomic map of human iris tissue

The human iris tissue is a thin, circular structure in the eye and it is made up of a pigmented epithelial structure. It is a protected internal organ of the eye, located behind the cornea and the aqueous humour. Iris serves main function to control the diameter, size of the pupil and regulation of ...

ORGANISM(S): Homo sapiens (Human)

2022-02-23 | PXD001299 | Pride

Human iris Brplc Eye proteome Vision

The proteome of normal human iris, ciliary body, retinal pigment epithelium, and choroid

ORGANISM(S): Homo sapiens (Human)

2016-02-04 | PXD002194 | Pride

Eye Ciliary body Choroid Iris Retinal pigment epithelium

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