Choroid - OmicsDI

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Clinical (1)

Organisms

Mus musculus (182)
Homo sapiens (158)
Bartonella quintana JK 31 (47)
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Onchocerca volvulus (47)
Klebsiella pneumoniae (47)
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Organisms

Mus musculus (162)
Homo sapiens (113)
Rattus norvegicus (15)
Gallus gallus (6)
Danio rerio (5)
Chlorocebus sabaeus (2)
Mus musculus musculus (2)
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Microcebus murinus (1)
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Canis lupus familiaris (1)
Sus scrofa (1)

Repository

ENA (366)
geo (260)
biostudies-arrayexpress (97)
pride (47)
EGA (19)
MassIVE (9)
MetaboLights (7)
EVA (4)
dbGaP (3)
iProX (3)
ExpressionAtlas (2)
jPOST (1)
PanoramaPublic (1)

Tissue

Cerebrospinal fluid (9)
Choroid (8)
Brain (7)
Retina (6)
Epithelial cell (6)
Cell culture (6)
Sclera (4)
Choroid plexus (3)
Retinal pigment epithelium (3)
Forebrain (2)
Forebrain and midbrain (1)
Temporal lobe (1)
Diencephalon (1)
Diencephalon and midbrain (1)
Forebrain fragment (1)
Medulla oblongata (1)
Pituitary and diencephalon (1)
Basal ganglion (1)
Hindbrain (1)
Spinal cord (1)
Telencephalon (1)
Pons (1)
Brain fragment (1)
Midbrain (1)
Hindbrain fragment (1)
Hindbrain without cerebellum (1)
Stomach (1)
Cerebral cortex (1)
Hippocampus (1)
Cerebellum (1)

Disease

Alzheimer's disease (3)
Hydrocephalus (2)
Age related macular degeneration (2)
Brain cancer (2)
Disease free (2)
Lymphoma (1)
Degeneration of macula and posterior pole (1)
Macular degeneration (1)
Choroid plexus carcinoma (1)
Choroid plexus papilloma (1)
Atypical choroid plexus papilloma (1)
Meningitis (1)
Neurodevelopmental abnormality (1)
Myopia (1)

Technology Type

Mass Spectrometry (47)
Shotgun proteomics (25)
Bottom-up proteomics (14)
Mass spectrometry assay (5)
Data-dependent acquisition (5)
Gel-based experiment (4)
Data-independent acquisition (3)
Mass spectrometry (2)
Top-down proteomics (2)
Illumina Genome Analyzer II, Illumina HiSeq 2000 (1)
Illumina HiSeq 2000 (1)
HDMSE (1)

Instrument Platform

Illumina NovaSeq 6000 (4)
Illumina HiSeq 2500 (3)
Illumina HiSeq 4000 (3)
- (3)
Liquid Chromatography MS - negative - hilic (3)
Impact (2)
LTQ Orbitrap Elite (2)
Orbitrap Fusion Lumos (2)
Liquid Chromatography MS - positive - hilic (2)
Liquid Chromatography MS - positive - reverse phase (2)
Liquid Chromatography MS - negative - reverse phase (2)
Dell precision T7500 (1)
Infinium MethylationEPIC v2.0 Kit (1)
Wizard Genomic DNA Purification Kit (1)
-- (1)
Illumina iScan (1)
Illumina NovaSeq X (1)
Illumina HiSeq 1000 (1)
BGISEQ-500 (1)
NextSeq 500 (1)
Illumina MiSeq (1)
LTQ Orbitrap Velos (1)
Orbitrap Fusion (1)
Q Exactive Plus (1)
Q Exactive HF-X (1)
Liquid Chromatography MS - Alternating (LC-MS (Alternating)) (1)
Liquid Chromatography MS - positive - reverse-phase (1)

Publication Date

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2020 (31)
2021 (26)
2015 (24)
2019 (23)
2013 (23)
2022 (21)
2012 (20)
2016 (19)
2014 (16)
2018 (15)
2017 (9)
2011 (8)
2010 (8)
2008 (8)
2009 (4)
2006 (1)
2003 (1)

CHEBI ID

CHEBI:22660 (2)
CHEBI:15741 (2)
CHEBI:18012 (2)
CHEBI:16951 (1)
CHEBI:16846 (1)
CHEBI:5589 (1)
CHEBI:10548 (1)
CHEBI:16679 (1)
CHEBI:5280807 (1)
CHEBI:28872 (1)
CHEBI:16237 (1)
CHEBI:10567 (1)
CHEBI:28868 (1)
CHEBI:16849 (1)
CHEBI:28863 (1)
CHEBI:28859 (1)
CHEBI:16429 (1)
CHEBI:28762 (1)
CHEBI:25314 (1)
CHEBI:28856 (1)
CHEBI:28784 (1)
CHEBI:16157 (1)
CHEBI:15827 (1)
CHEBI:25057 (1)
CHEBI:58195 (1)
CHEBI:28848 (1)
CHEBI:28840 (1)
CHEBI:28737 (1)
CHEBI:64701 (1)
CHEBI:28788 (1)

Metabolite Name

Hypoxanthine (3)
Phenol, 2-[4-[(3,5-dichlorophenyl)amino]-6-methyl-2-pyrimidinyl]- (2)
4-Amino-2-oxo-1,2-dihydropyrimidine-5-carboxylic acid (2)
Coniferin (2)
Arachidonic sulfonic acid (2)
4(5H)-Thiazolone, 5-(6-quinolinylmethylene)-2-[(2-thienylmethyl)amino]-, (5Z)- (2)
7-Hydroxy-6-methoxy-3-methyl-5-(propan-2-ylidene)furo[2,3,4-de]chromen-2(5H)-one (2)
Lys-Asp (2)
GDP-mannose (2)
Gamma-Glutamylglutamine (2)
Adenylsuccinic acid (2)
3-Methyl-1H-pyrazole-4-carbaldehyde (2)
LysoPE(20:4(5Z,8Z,11Z,14Z)/0:0) (2)
Naringenin (2)
6-Benzyl-3-butan-2-yl-9-(7-hydroxy-6-oxooctyl)-1,4,7,10-tetrazabicyclo[10.4.0]hexadecane-2,5,8,11-tetrone (2)
MES (2)
LPG(18:1(9Z)) (2)
2-Hydroxy-3-methylbutyric acid (2)
Ile-Leu (2)
Ala-Glu (2)
Trigonelline (2)
Uracil (2)
Valine (2)
2-Aminopurine (2)
Pyroglutamic acid (2)
N-Acetylglutamic acid (2)
Glucose 6-phosphate (2)
Citrulline (2)
Pantothenol (2)
Indolelactic acid (2)

First Public Date

2025 (65)
2024 (52)
2026 (40)
2014 (40)
2023 (36)
2020 (26)
2021 (25)
2019 (25)
2022 (20)
2017 (10)
2016 (9)
2018 (8)
2015 (8)
2013 (2)

Study status

Recruiting (1)

Study type

Transcription profiling by array (65)
RNA-seq of coding RNA (10)
Comparative genomic hybridization by array (4)
Methylation profiling by array (4)
Single nucleus RNA sequencing (3)
RNA-seq of coding RNA from single cells (3)
Unknown experiment type (2)
MicroRNA profiling by high-throughput sequencing (1)
Animal - High-throughput sequencing (1)
Cell line - High-throughput sequencing (1)
ChIP-seq (1)
MicroRNA profiling by array (1)
RNA-seq of non coding RNA (1)
Observational (1)

Release Date

2022 (232)
2025 (220)
2023 (197)
2024 (191)
2021 (182)
2020 (167)
2019 (118)
2018 (107)
2015 (84)
2017 (82)
2016 (78)
2014 (58)
2013 (57)
2012 (53)
2026 (36)
2011 (26)
2009 (24)
2010 (22)
2008 (16)
2006 (12)
2007 (7)
2005 (4)
2003 (4)
2000 (3)
1997 (3)
2004 (2)
2002 (2)
1998 (2)

Lab affiliation

Affiliated Eye Hospital of Shandong University of Traditional Chinese Medicine (4)
ULB Neuroscience Institute (UNI) Université Libre de Bruxelles (ULB) B-6041 Gosselies, Belgium. (2)
VIB Department of Medical Protein Research, UGent Proteome Analysis and Bioinformatics Unit A. Baertsoenkaai 3 B9000 Gent Belgium (2)
Wilmer Eye Institute, Smith Building, M015, 400 N. Broadway, Baltimore, MD 21287 (2)
University of Pittsburgh School of Medicine, Ophthalmology department (1)
VisionGift, Research 2201 SE 11th Ave Portland, Oregon 97214 USA (1)
Department of Ophthalmology, LMU University Hospital, LMU Munich, Munich, Germany (1)
Duke University, Albert Eye Research Institute (1)
Eye & Vison Health, Flinders University School of Medicine Flinders Medical Center Flinders University Australia (1)
Department of Psychiatry and Neuropsychology, Alzheimer Centrum Limburg, School for Mental Health and Neuroscience, Maastricht University, Maastricht, the Netherlands (1)
1Department of Neurosurgery, Yale School of Medicine, New Haven, CT, USA. Department of Neurosurgery, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts, USA Broad Institute of Harvard and MIT, Cambridge, Massachusetts, USA (1)
Department of Infectious Diseases, Immunology and Sexual Health and Department of Medicine, St George Hospital, University of New South Wales, 2 South Street, Kogarah, Sydney, NSW 2217, Australia (1)
Ph. D, HDR Responsable de l’équipe « Neurobiologie intégrative de la reproduction »- ER2 NIGER UMR 7247 INRA-CNRS-Univ. Tours-IFCE Centre INRA de Tours, PRC F-37380 Nouzilly France (1)
Director UAB Proteomics Facility (1)
Boston Childrens Hospital Harvard Medical School (1)
1Department of Ophthalmology, Johns Hopkins University School of Medicine, Baltimore, MD (1)
Wilmer Eye Institute, Smith Building, M015, 400 N. Broadway, Baltimore, MD 21287. Tel. (410) 532-2123, Fax (410) 502-1753 (1)
Department of Biochemistry and Molecular Biology University of Southern Denmark (1)
Tumor Biology Research Program, Basic Research Unit, Research Department, Children's Cancer Hospital Egypt 57357 (1)
CEITEC-MU, Masaryk University, Kamenice 5, 625 00, Brno, Czech Republic (1)
Vinit B. Mahajan M.D., Ph.D., Byers Eye Institute, Department of Ophthalmology, Stanford University, Palo Alto, CA, 94304 USA (vinit.mahajan@stanford.edu). Phone: 650.723.6995. Fax: 650.498.1528. (1)
Cardeza Center for Vascular Biology Sidney Kimmel Medical College Thomas Jefferson University (1)
VIB Center for Inflammation Research, VIB, Ghent, Belgium Department of Biomedical Molecular Biology, Ghent University, Ghent, Belgium (1)
Klinik für Kinder- und Jugendmedizin, Medizinische Fakultät Mannheim, Germany (1)
Singapore Eye Research Institute, Singapore National Eye Centre, Duke-NUS, Medical School, Singapore, Singapore (1)
1Korea Brain Research Institute (1)
Evandro Chagas National Institute of Infectious Diseases (INI) - Oswaldo Cruz Foundation (FIOCRUZ) (1)
Department of Biochemistry and Molecular Biology, University of Southern Denmark, Odense, Denmark (1)
Pysiological Genomics, LMU Muenchen, Germany (1)
Department of Ophthalmology, Johns Hopkins University School of Medicine (1)

Location

United States (1)

Keyword

Genome analysis (1)
Genetic modifiers (1)
Next generation sequencing (NGS) (1)
Heritable disease (1)
Cancer risk (1)
Genetic predisposition (1)
Genetic counseling (1)
DNA (1)

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mouse RPE/choroid age comparison - ATLAS arrays

Young mice were compared to old mice (2 month vs 24 month) to determine gene changes that occur with aging in the mouse retinal pigmented epithelium/choroid of the eye. Keywords = retinal pigmented epithelium Keywords = aging Keywords = choroid

ORGANISM(S): Mus musculus

2010-06-05 | E-GEOD-565 | biostudies-arrayexpress

The proteome of normal human iris, ciliary body, retinal pigment epithelium, and choroid

The iris is a fine structure that controls the amount of light that enters the eye. The ciliary body controls the shape of the lens and produces aqueous humor. The retinal pigment epithelium and choroid (RPE/choroid) are essential in supporting the retina and absorbing light energy that enters the e...

ORGANISM(S): Homo Sapiens (ncbitaxon:9606)

2017-11-29 | MSV000081766 | MassIVE

Gene expression profiles obtained from laser-microdissected human choroid plexus papilloma cells

Gene expression profiles generated from human tumor cells laser-microdissected from surgical samples of seven choroid plexus papillomas (Grade I WHO) as eight samples of epithelial cells lasermicrodissected from normal choroid plexus obtained at autopsy. Choroid plexus tumors are rare pediatric brai...

ORGANISM(S): Homo sapiens

2009-02-01 | E-GEOD-14098 | biostudies-arrayexpress

Genome-wide analysis and comparison of E15 and adult rat lateral ventricular choroid plexus epithelial cells.

Transcriptome analysis of lateral ventricular choroid plexus epithelial cells of embryonic day 15 (E15) and adult control Sprague-Dawley rats. We analyzed total RNA extracted from plexus epithelial cells from 6 pooled samples (3 E15, 3 adult) using the Illumina HiSeq 2000 platform.

ORGANISM(S): Rattus norvegicus

2013-09-16 | E-GEOD-44072 | biostudies-arrayexpress

Gene expression study in choroid plexus

The choroid plexus (CP) constitutes one of the blood–brain barriers – the blood cerebrospinal fluid barrier. It is formed by a monolayer of epithelial cells located within the brain ventricles and in addition to be responsible for the formation of the cerebrospinal fluid (CSF) is ideally positioned ...

ORGANISM(S): Mus musculus

2010-08-19 | E-GEOD-23714 | biostudies-arrayexpress

In vivo Gene Expression Profiling of RPE/choroid Post-Intravitreal Injections of Dexamethasone and Triamcinolone at Clinically Relevant Time Points for Patient Care

PURPOSE To identify retinal pigment epithelial (RPE)/choroid genes and their relevant expression pathways affected by intravitreal injections of dexamethasone and triamcinolone acetonide in mice at clinically relevant time points for patient care. METHODS Differential gene expression of over 3...

ORGANISM(S): Mus musculus

2016-08-01 | E-GEOD-49872 | biostudies-arrayexpress

Gene expression data from lateral ventricle choroid plexuses of developing and adult rats

Choroid plexuses (CP) develop early during development. They form a barrier between the blood and the cerebrospinal fluid, and fulfill important protective and nutritive functions. We used Affymetrix microarrays to assess whether CP of the lateral ventricles (LVCP) have similar functions in developi...

ORGANISM(S): Rattus norvegicus

2013-09-17 | E-GEOD-44056 | biostudies-arrayexpress

A proteomic map of human choroid tissue

The choroid is the vascular layer situated between the outer sclera and the inner retina. Together with the ciliary body and the iris it forms the uvea. Because of its rich blood supply it is also called the nutritive layer and it supplies oxygen and nutrition to the retinal pigment epithelium and t...

ORGANISM(S): Homo sapiens (Human)

2018-04-25 | PXD002273 | Pride

In Vitro Transcriptome Analysis of Porcine Plexus Epithelial Cells in Response to Streptococcus suis: Functions of the Choroid Plexus in Antimicrobial Defense

We used microarrays to detail the global gene expression changes following apical infection of porcine choroid plexus epithelial cells (PCPEC) with Streptococcus suis (S. suis) We compared PCPEC either un-treated or infected with wild-type S. suis strain 10 or the acapsular strain 10cpsDEF, respecti...

ORGANISM(S): Sus scrofa

2011-08-14 | E-GEOD-23751 | biostudies-arrayexpress

The transcription factor Otx2 regulates choroid plexus development and function

The choroid plexuses (ChPs) are the main regulators of cerebrospinal fluid (CSF) composition and thereby also control the composition of a principal source of signaling molecules that is in direct contact with neural stem cells in the developing brain. The regulators of ChP development mediating the...

ORGANISM(S): Mus musculus

2013-02-05 | E-GEOD-27630 | biostudies-arrayexpress

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