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ProteomicsGenome-wide effects of the antimicrobial peptide apidaecin on translation termination
Proline-rich antimicrobial peptide apidaecin (Api) inhibits bacterial protein synthesis in a distinctive way. In vitro biochemical and structural studies showed that Api binds in the nascent peptide exit tunnel of the ribosome that has completed translation of the gene and has released the newly-syn...
ORGANISM(S): Escherichia coli 
2020-10-05 | PXD019012 | Pride
Apidaecin Translation termination Lc-ms Peptide E. coli 
GenomicsSequence diversity of apidaecin-like peptides arresting the terminating ribosome
Sequence diversity of apidaecin-like peptides arresting the terminating ribosome
PRJNA1124079 | ENA
ProteomicsAntimicrobial peptides of the apidaecin family inhibit the bacterial ribosome by multimodal mechanisms involving three different sites on the large ribosomal subunit
Proline-rich antimicrobial peptides (PrAMPs) inhibit bacterial ribosomes by binding to the polypeptide exit tunnel (PET) near the peptidyl transferase center. Api137, an optimized derivative of honeybee apidaecin, traps the release factor (RF) at the ribosome, thereby arresting the ribosomes at stop...
ORGANISM(S): Escherichia Coli 
PXD044892 | panorama
UnknownStructure-Activity Relationships of the Antimicrobial Peptide Natural Product Apidaecin.
Not available
S-EPMC10768847 | biostudies-literature
GenomicsGenome-wide effects of the antimicrobial peptide apidaecin on translation termination
Genome-wide effects of the antimicrobial peptide apidaecin on translation termination
PRJNA630973 | ENA
UnknownPorphyrin-apidaecin conjugate as a new broad spectrum antibacterial agent.
Not available
S-EPMC4007951 | biostudies-literature
UnknownConstruction and Characterization of T7 Bacteriophages Harboring Apidaecin-Derived Sequences.
Not available
S-EPMC9221748 | biostudies-literature
UnknownHigh-level heterologous production and Functional Secretion by recombinant Pichia pastoris of the shortest proline-rich antibacterial honeybee peptide Apidaecin.
Not available
S-EPMC5674047 | biostudies-literature
UnknownIn vivo target exploration of apidaecin based on Acquired Resistance induced by Gene Overexpression (ARGO assay).
Not available
S-EPMC5610309 | biostudies-literature
UnknownSequence diversity of apidaecin-like peptides arresting the terminating ribosome.
Not available
S-EPMC11347161 | biostudies-literature
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