Sort   by:  
 Page size 
TranscriptomicsRegulation of Pattern Recognition Receptors by the Apolipoprotein A-I Mimetic Peptide 4F
The apolipoprotein A-I (apoA-I) mimetic peptide 4F displays prominent anti-inflammatory properties, including the ability to reduce vascular macrophage content. Macrophages are a heterogenous group of cells, represented by two principal phenotypes, the classically activated M1 macrophage and an alt...
ORGANISM(S): Homo sapiens 
2012-09-30 | E-GEOD-36933 | biostudies-arrayexpress
ProteomicsApolipoprotein A-II Increases Cholesterol Efflux Capacity of Mature High-Density Lipoproteins Via the Apolipoprotein A-I C-terminus
Samples were processed using Global and Limited Proteolysis (LiP). Peptides and proteins were identified using MaxQuant (v1.6.17.0), then summarized using R package RomicsProcessor.
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2024-07-29 | MSV000095479 | MassIVE
GenomicsInsulin fused to apolipoprotein A-I
Insulin fused to apolipoprotein A-I
PRJNA671860 | ENA
GenomicsApolipoprotein A-I Influences The Transcriptional Profile Of Fatty Liver In Apolipoprotein E Knockout Mice
Apolipoprotein A-I Influences The Transcriptional Profile Of Fatty Liver In Apolipoprotein E Knockout Mice
PRJNA1146900 | ENA
ProteomicsLong-term liver expression of an apolipoprotein A-I mimetic peptide attenuates IFNα-induced inflammation and promotes antiviral activity
Apolipoprotein A-I mimetic peptides are amphipathic alpha-helix peptides that display similar functions to apolipoprotein A-I. Preclinical and clinical studies have demonstrated the safety and efficacy of apolipoprotein A-I mimetic peptides in multiple indications associated with inflammatory proces...
ORGANISM(S): Mus musculus (Mouse) 
2021-09-09 | PXD023281 | Pride
Adeno-associated virus Antiviral Apolipoprotein a-i mimetic peptide Liver Type i ifn 
GenomicsApolipoprotein A-I Anti-tumor Activity Targets Cancer Cell Metabolism
Apolipoprotein A-I Anti-tumor Activity Targets Cancer Cell Metabolism
PRJNA565788 | ENA
GenomicsApolipoprotein A-I mimetic peptide L37pA attenuates IFNα-induced inflamation and promotes antiviral activity
Apolipoprotein A-I mimetic peptide L37pA attenuates IFNα-induced inflamation and promotes antiviral activity
PRJNA682989 | ENA
ProteomicsSite-specific 5-hydroxy-tryptophan incorporation into apolipoprotein A-I impairs cholesterol efflux activity and high density lipoprotein biogenesis
We used genetic code expansion technology with an engineered Saccharomyces cerevisiae tryptophanyl tRNA- synthetase:suppressor tRNA pair in Escherichia coli, to directly insert the non- canonical amino acid 5-OH tryptophan (5-OHTrp) at position 72 in human apoA-I. Characterization of recombinant hum...
ORGANISM(S): Homo sapiens (Human) 
2020-03-02 | PXD017226 | Pride
Plasma Apolipoprotein a-i 5-oh-trp Human 
ProteomicsThe pattern of apolipoprotein A-I lysine carbamylation as a probe of the environment within human atherosclerotic aorta
Protein lysine residue carbamylation is an irreversible post-translational modification, resulting in the generation of protein-bound homocitrulline (N--carbamyllysine). Carbamylation alters protein structure and can thus also alter protein function because of the loss of the charged -amino lysine m...
ORGANISM(S): Homo sapiens (Human) 
2022-04-06 | PXD027881 | Pride
High density lipoprotein Cardiovascular disease Urea. Oxidation Apolipoprotein a-i Carbamylation Cyanate Homocitrulline Myeloperoxidase 
TranscriptomicsMicroarray gene expression profiling of heart failure induced in apolipoprotein E-deficient mice by treatment with rosiglitazone
The anti-diabetic drug and agonist of the peroxisome proliferator-activated receptor gamma (Pparg), rosiglitazone, was recently withdrawn in many countries because the drug use was associated with an increased risk of heart failure. To investigate underlying pathomechanisms, we chose 6-month-old apo...
ORGANISM(S): Mus musculus 
2011-03-18 | E-GEOD-28031 | biostudies-arrayexpress
Sort   by:  
 Page size