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ProteomicsNeutrophil myeloperoxidase harbors distinct site-specific peculiarities in its glycosylation
Glycoproteomics analysis of human neutrophil myeloperoxidase from two independent donor pools.
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
MSV000084281 | MassIVE
GenomicsMyeloperoxidase gene deletion in dextran sodium sulfate-induced colitis
Myeloperoxidase gene deletion in dextran sodium sulfate-induced colitis
PRJEB66447 | ENA
ProteomicsThe Bimodal Sugar Code of Neutrophil Myeloperoxidase
Myeloperoxidase (MPO), an important diprotomeric glycoprotein in neutrophil-mediated immunity, produces microbicidal hypohalous acids, but the underpinning glycobiology remains elusive. Deep characterisation of neutrophil-derived MPO (nMPO) using advanced mass spectrometry demonstrated that under-pr...
ORGANISM(S): Homo sapiens (Human) 
2021-03-07 | PXD021131 | Pride
Biosynthesis Granulopoiesis Degranulation Neutrophil Activity : myeloperoxidase N-glycosylation N-acetyl-β-d-glucosamine Ceruloplasmin Granule Inhibition 
TranscriptomicsThe effect of MPO inhibitor on the gene expression profiles in HL-60 cell lines exposed to 1, 2, 4,-benzenetriol
To reveal the gene expression profile changes after exposure to BT, one of benzene metabolites, with or without ABAH, a myeloperoxidase (MPO) inhibitor, and to elucidate how MPO is involved in myelotoxicity of BT, we performed microarray analysis. HL-60 cells suspended in RPMI 1640 containing with 1...
ORGANISM(S): Homo sapiens 
2013-12-01 | E-GEOD-50805 | biostudies-arrayexpress
ProteomicsMyeloperoxidase is a Critical Mediator of Anthracycline-induced Cardiomyopathy
The anthracycline doxorubicin is a commonly used chemotherapeutic drug that induces cardiomyopathy in almost 10% of patients. The aim of this study was to examine the role of the leukocyte-derived enzyme Myeloperoxidase (MPO) in pathogenesis of anthracycline-induced Cardiomyopathy (AICM). We perform...
ORGANISM(S): Mus musculus (Mouse) 
2023-08-30 | PXD037524 | Pride
Cardiotoxicity Polymorphonuclear neutrophils Aicm Mpo Doxorubicin 
UnknownMyeloperoxidase Mediates Postischemic Arrhythmogenic Ventricular Remodeling.
Not available
S-EPMC5482785 | biostudies-literature
ProteomicsComprehensive quantification of modifications of human and mouse myeloperoxidase by LC-MSMS
Anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) is a systemic and refractory disease, characterized by necrotizing small to medium vessel vasculitides. AAV constitutes three distinct disorders: microscopic polyangiitis (MPA), granulomatosis with polyangiitis (GPA) (formerly k...
ORGANISM(S): Homo sapiens (Human) Mus musculus (Mouse) 
2025-04-21 | PXD050920 | Pride
Human Lc-msms Oxidative modification Mouse Myeloperoxidase 
UnknownTriazolopyrimidines identified as reversible myeloperoxidase inhibitors.
Not available
S-EPMC6071758 | biostudies-literature
UnknownNanoparticle effect on neutrophil produced myeloperoxidase.
Not available
S-EPMC5773199 | biostudies-literature
UnknownMyeloid expression of the anti-apoptotic protein Mcl1 is required in anti-myeloperoxidase vasculitis but myeloperoxidase inhibition is not protective.
Not available
S-EPMC10166712 | biostudies-literature
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