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MetabolomicsEvolutionary novelty of Apolipoprotein D facilitates metabolic plasticity in lepidopteran wings

Understanding metabolic plasticity of animal evolution is a fundamental challenge in evolutionary biology. Owing to the diversification of insect wing morphology and dynamic energy requirements, the molecular adaptation mechanisms underlying the metabolic pathways in wing evolution remain largely...

2026-03-29 | MTBLS11285 | MetaboLights
MetabolomicsEvolutionary novelty of Apolipoprotein D facilitates metabolic plasticity in lepidopteran wing

Understanding metabolic plasticity of animal evolution is a fundamental challenge in evolutionary biology. Owing to the diversification of insect wing morphology and dynamic energy requirements, the molecular adaptation mechanisms underlying the metabolic pathways in wing evolution remain largely...

2026-03-29 | MTBLS4308 | MetaboLights
ProteomicsMS analyses of mouse VLDL from WT and ApoA5 (Apolipoprotein A-V) knockout mice
The impact of APOA5 on VLDL composition and its potential to alter VLDL metabolism in other ways remains poorly understood. To address this, we investigated the influence of APOA5 on the VLDL proteome. We used VLDL from Apoa5 knockout (KO) and wild-type (WT) mice, for mass spectrometry utilizing two...
ORGANISM(S): Mus musculus (Mouse) 
2025-11-24 | PXD065274 | Pride
Mouse Knockout Vldl Apolipoprotein a-v 
TranscriptomicsInterleukin-7 promotes monocyte/macrophage arrest on endothelial cells
Background: It is recognized that atherosclerosis can regresses at least in animal models. However, little is known about the mechanisms. We induced regression of advanced atherosclerosis in apolipoprotein E deficient (APOE­/­) mice and studied underlying mechanisms. Unexpectedly, our study led to t...
ORGANISM(S): Mus musculus 
2009-10-01 | E-GEOD-15914 | biostudies-arrayexpress
TranscriptomicsMicroarray gene expression profiling of heart failure induced in apolipoprotein E-deficient mice by treatment with rosiglitazone
The anti-diabetic drug and agonist of the peroxisome proliferator-activated receptor gamma (Pparg), rosiglitazone, was recently withdrawn in many countries because the drug use was associated with an increased risk of heart failure. To investigate underlying pathomechanisms, we chose 6-month-old apo...
ORGANISM(S): Mus musculus 
2011-03-18 | E-GEOD-28031 | biostudies-arrayexpress
UnknownApolipoprotein A-V gene therapy for disease prevention / treatment: a critical analysis.
Not available
S-EPMC4820885 | biostudies-literature
UnknownHigh density lipoprotein promotes nascent apolipoprotein A-V secretion from mRNA transfected cells.
Not available
S-EPMC6467731 | biostudies-literature
UnknownAn apolipoprotein A-V gene SNP is associated with marked hypertriglyceridemia among Asian-American patients.
Not available
S-EPMC2444008 | biostudies-literature
UnknownEndocytosis of apolipoprotein A-V by members of the low density lipoprotein receptor and the VPS10p domain receptor families.
Not available
S-EPMC2533778 | biostudies-literature
MetabolomicsApolipophorin-III modulates antiviral defense in Bombyx mori: an integrated transcriptomic and lipidomic analysis of its inhibitory role against BmNPV infection.

The silkworm (Bombyx mori) is an economically important insect and a lepidopteran model organism. Controlling viral infections is crucial for the sustainable development of sericulture. Bombyx mori nucleopolyhedrovirus (BmNPV) infection can cause large-scale mortality in silkworm populations. Ins...

2025-12-03 | MTBLS13447 | MetaboLights
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