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ProteomicsIdentification of extracellular substrates of apoptotic caspases-3 and -7 cleaved from cell membrane of MDA-MB-231 cells
Investigate whether apoptotic caspases-3 and -7 can cleave membrane-bound proteins from breast cancer MDA-MB-231 cells.
ORGANISM(S): Homo sapiens (Human) 
2025-04-18 | PXD061399 | Pride
Apoptotic caspases Gel-based proteomics Shedding Mda-mb-231 cells Degradomics 
ModelsCorbat2021 - Apoptotic Reaction Model.models
Apoptotic Reaction Model is an ordinary differential equation model describing every species in the apoptotic cascade and trained to simulate experiments with extrinsic or intrinsic stimuli. It is based on the model introduced by Albeck et al. 2008 and contains a missing feedback between effector ca...
2021-05-26 | MODEL2105210001 | BioModels
Not Peer Reviewed 
UnknownTargeting apoptotic caspases in cancer.
Not available
S-EPMC7155770 | biostudies-literature
UnknownPlasma Membrane Localization of Apoptotic Caspases for Non-apoptotic Functions.
Not available
S-EPMC5972739 | biostudies-literature
UnknownActivation of Pro-apoptotic Caspases in Non-apoptotic Cells During Odontogenesis and Related Osteogenesis.
Not available
S-EPMC5845891 | biostudies-literature
TranscriptomicsApoptotic caspases prevent the induction of type I interferons by mitochondrial DNA
RNA sequencing of wild-type or Interferon Alpha receptor 1 Knockout MEF cells treated with DMSO or the Broad-spectrum Caspase Inhibitor Q-VD-OPh The mechanism by which cells undergo death determines whether dying cells trigger inflammatory responses or remain immunologically silent. Mitochondria pla...
ORGANISM(S): Mus musculus 
2014-12-03 | E-GEOD-63794 | biostudies-arrayexpress
TranscriptomicsApoptotic caspases prevent the induction of type I interferons by mitochondrial DNA
RNA sequencing of wild-type or Interferon Alpha receptor 1 Knockout MEF cells treated with DMSO or the Caspase Inhibitor Q-VD-OPh. The mechanism by which cells undergo death determines whether dying cells trigger inflammatory responses or remain immunologically silent. Mitochondria play a central ro...
ORGANISM(S): Mus musculus 
2014-12-03 | GSE63794 | GEO
UnknownExogenous Introduction of Initiator and Executioner Caspases Results in Different Apoptotic Outcomes.
Not available
S-EPMC8385707 | biostudies-literature
UnknownApoptotic caspases suppress mtDNA-induced STING-mediated type I IFN production.
Not available
S-EPMC4520319 | biostudies-literature
UnknownHuman initiator caspases trigger apoptotic and autophagic phenotypes in Saccharomyces cerevisiae.
Not available
S-EPMC2647587 | biostudies-literature
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