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The gastrointestinal tract may be a site of origin for α-synuclein (α-syn) pathology in idiopathic Parkinson’s disease (PD), and an abundance of aggregated α-syn has recently been demonstrated in both the healthy and PD appendix. However, the molecular changes that enable gut α-syn aggregates to con...
ORGANISM(S): Homo sapiens (Human) 
2020-02-18 | PXD015079 | Pride
The gastrointestinal tract may be a site of origin for α-synuclein (α-syn) pathology in idiopathic Parkinson’s disease (PD), and an abundance of aggregated α-syn has recently been demonstrated in both the healthy and PD appendix. However, the molecular changes that enable gut α-syn aggregates to con...
ORGANISM(S): Homo sapiens (Human) 
2021-07-06 | PXD021757 | Pride
Appendix Metagenome
Human Appendix Microbiome
Pseudomyxoma peritonei (PMP) is a subtype of mucinous adenocarcinoma of the appendix, We compared N-linked glycan profiles of PMP tissues to those of normal appendix. N-glycosidase F liberated N-glycan profiles of eight normal appendix samples and eight low-grade and eight high-grade PMP specimens w...
ORGANISM(S): Homo sapiens (Human) 
2018-08-03 | PXD010086 | Pride
Pathogenesis elucidation of Ulcerative Colitis Focusing on Appendix Immunity
An appendix to the published Gaulton et al. work (PMID: 20118932; E-GEOD-17616). In the original paper, the authors note that samples 1 and 2 are not as pure as the third sample. This appendix provides FAIRE-Seq data obtained from a purified islet sample to replace the problematic published data. Th...
ORGANISM(S): Homo sapiens 
Background: Appendix immunity may be involved in the pathogenesis of ulcerative colitis (UC), but the mechanism is not yet understood. In this study, we aimed to characterize immune cells in the appendix of UC patients. Method: We performed scRNA-seq on appendix cells from UC and non-UC patients. Re...
ORGANISM(S): Homo sapiens 
2026-07-29 | GSE284191 | GEO
Top Down Proteomics Data associated with detection of synuclein proteoforms in The Vermiform Appendix Contributes to the Development of Parkinsons Disease
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2018-05-09 | MSV000082353 | MassIVE
Molecular Profiling of the Appendix in Pediatric Inflammatory Bowel Diseases
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