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Archaea are ubiquitous prokaryotes with a wide range of habitats, important roles in ecology, biotechnology and potentially even human health. Despite that, our understanding of archaeal cell biology is still rather limited, partially because the application of systems biology approaches is lacking ...
ORGANISM(S): Haloferax volcanii DS2 
2020-05-11 | PXD014974 | Pride
Cell shape plays a crucial role in microbial survival. While Haloferax volcanii, a model haloarchaeon, forms rods and disks, depending on environmental conditions, little is known about mechanisms underpinning archaeal cell-shape determination. We identified mutants that exclusively form rods and ca...
ORGANISM(S): Haloferax volcanii (Halobacterium volcanii) Archaea 
2024-02-17 | PXD040781 | Pride
Quorum sensing (QS) is a mechanism of intercellular communication that enables microbes to alter gene expression and adapt to the environment. While QS has been extensively studied in bacteria, little is known about cell-cell communication in archaea. We could show that for Haloferax volcanii, the t...
ORGANISM(S): Haloferax volcanii (Halobacterium volcanii) Archaea 
2025-06-17 | PXD059278 | Pride
We performed an in-depth proteome analysis of the haloarchaeal model organism Haloferax volcanii under standard, low and high salt and low and high temperature conditions using label-free mass spectrometry. Qualitative analysis of protein identification data from high pH/reversed phase fractionated ...
ORGANISM(S): Haloferax volcanii DS2 
2019-09-04 | PXD011056 | Pride
Rhomboids are conserved intramembrane serine proteases involved in cell signaling processes. Their role in prokaryotes is scarcely known and remains to be investigated in Archaea. We previously constructed a rhomboid homologue deletion mutant (ΔrhoII) in Haloferax volcanii, which showed reduced moti...
ORGANISM(S): Haloferax volcanii DS2 
2020-05-14 | PXD011218 | Pride
Histones and associated chromatin proteins have essential functions in eukaryotic genome organization and regulation. Despite this fundamental role in eukaryotic cell biology, we lack a phylogenetically-comprehensive understanding of chromatin evolution. Here, we combine comparative proteomics and g...
ORGANISM(S): Acanthamoeba castellanii Sycon ciliatum Phytophthora infestans Thecamonas trahens Dictyostelium discoideum (Slime mold) Chlamydomonas reinhardtii Physcomitrella Nitrososphaera viennensis Bigelowiella natans Homo sapiens (Human) Methanobrevibacter cuticularis Gefionella okellyi Corallochytrium limacisporum Guillardia theta Naegleria gruberi Capsaspora owczarzaki Emiliania huxleyi Spizellomyces punctatus Methanospirillum stamsii Thalassiosira pseudonana Fabomonas tropica 
2022-08-12 | PXD031991 | Pride
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