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ProteomicsE3 ligase AMFR regulates ARL6IP1 Ubiquitination in cells
ER-resident membrane-shaping proteins with central reticulon homology domains (RHDs) have been associated with neurodegenerative disorders such as ARL6IP1 and FAM134B.Mutations in ARL6IP1 cause SPG61, a neurodegenerative disorder characterized by progressive leg spasticity (hereditary spastic parapl...
ORGANISM(S): Homo sapiens (Human) 
2023-06-19 | PXD039184 | Pride
Amfr Arl6ip1 ubiquitination 
ProteomicsARL6IP1 and FAM134B forms a complex
ER-resident membrane-shaping proteins with central reticulon homology domains (RHDs) have been associated with neurodegenerative disorders such as ARL6IP1 and FAM134B.Mutations in ARL6IP1 cause SPG61, a neurodegenerative disorder characterized by progressive leg spasticity (hereditary spastic parapl...
ORGANISM(S): Homo sapiens (Human) 
2023-06-19 | PXD032720 | Pride
Venus arl6ip1 and heterodimer fam134b 
ProteomicsARL6IP1 is an interacting partner of the ER-phagy receptor FAM134B
ER-resident membrane-shaping proteins with central reticulon homology domains (RHDs) have been associated with neurodegenerative disorders such as ARL6IP1 and FAM134B.Mutations in ARL6IP1 cause SPG61, a neurodegenerative disorder characterized by progressive leg spasticity (hereditary spastic parapl...
ORGANISM(S): Homo sapiens (Human) 
2023-06-19 | PXD032718 | Pride
Ha fam134b Arl6ip1 
UnknownZebrafish arl6ip1 is required for neural crest development during embryogenesis.
Not available
S-EPMC3298456 | biostudies-literature
UnknownARL6IP1 gene delivery reduces neuroinflammation and neurodegenerative pathology in hereditary spastic paraplegia model.
Not available
S-EPMC10630151 | biostudies-literature
UnknownARL6IP1 mediates small-molecule-induced alleviation of Alzheimer pathology through FXR1-dependent BACE1 translation initiation.
Not available
S-EPMC10235968 | biostudies-literature
UnknownOLFM4 depletion sensitizes gallbladder cancer cells to cisplatin through the ARL6IP1/caspase-3 axis.
Not available
S-EPMC8728528 | biostudies-literature
UnknownRNA binding protein HuD promotes autophagy and tumor stress survival by suppressing mTORC1 activity and augmenting ARL6IP1 levels.
Not available
S-EPMC8744261 | biostudies-literature
UnknownLiver X receptor-agonist treatment rescues degeneration in a Drosophila model of hereditary spastic paraplegia.
Not available
S-EPMC8961908 | biostudies-literature
UnknownHeteromeric clusters of ubiquitinated ER-shaping proteins drive ER-phagy.
Not available
S-EPMC10247384 | biostudies-literature
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