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ProteomicsDissecting the molecular diversity and commonality of bovine and human treponemes identifies key survival and adhesion mechanisms
Here, we report the first complete genomes of three cultivable treponeme species from bovine digital dermatitis (DD) skin lesions, two comparative human treponemes and a bovine gastrointestinal (GI) isolate. Key genomic differences between bovine and human treponemes implicate microbial mechanisms t...
ORGANISM(S): Treponema sp. T19 Treponema pedis Treponema ruminis Treponema phagedenis Treponema medium Treponema sp. T320A 
2021-03-16 | PXD022419 | Pride
Bovine digital dermatitis Treponemes Shotgun lc msms 
ProteomicsFaustovirus global proteome - Faustovirus, an asfarvirus-related new lineage of giant viruses infecting amoebae
Global proteome study of two protein extracts of purified Faustovirus, using a bi dimensionnal nanoLC fractionnation combined to a Synapt G2 Si HDMSe monitoring enabling ion mobility
ORGANISM(S): Faustovirus 
2015-04-22 | PXD001858 | Pride
Nano2dlc-ms/ms Faustovirus Ion mobility 
ProteomicsRickettsia raoultii intra cellular bacteria global proteome
Semi quantitative intracellular bacteria proteome using a 2D nanoLC-M/MS analysis system enabling a maximum sample exploration. This setup was helpful to analyse this complex sample composed of peptides from the studied bacteria and its host. Sample was doped before injection in order to calculate p...
ORGANISM(S): Rickettsia raoultii Xenopus laevis (African clawed frog) 
2018-10-25 | PXD003193 | Pride
Hdmse Xenopus laevis Rickettsia Hi3 
ProteomicsRickettsia conorii intra cellular bacteria global proteome
Semi quantitative intracellular bacteria proteome using a 2D nanoLC-M/MS analysis system enabling a maximum sample exploration. This setup was helpful to analyse this complex sample composed of peptides from the studied bacteria and its host. Sample was doped before injection in order to calculate p...
ORGANISM(S): Rickettsia conorii (strain ATCC VR-613 / Malish 7) 
2018-10-25 | PXD003194 | Pride
Hdmse Xenopus laevis Rickettsia Hi3 
ProteomicsRickettsia massiliae intra cellular bacteria global proteome
Semi quantitative intracellular bacteria proteome using a 2D nanoLC-M/MS analysis system enabling a maximum sample exploration. This setup was helpful to analyse this complex sample composed of peptides from the studied bacteria and its host. Sample was doped before injection in order to calculate p...
ORGANISM(S): Rickettsia massiliae (strain Mtu5) Xenopus laevis (African clawed frog) 
2018-10-25 | PXD003197 | Pride
Hdmse Xenopus laevis Rickettsia Hi3 
ProteomicsRickettsia slovaca intra cellular bacteria global proteome
Semi quantitative intracellular bacteria proteome using a 2D nanoLC-M/MS analysis system enabling a maximum sample exploration. This setup was helpful to analyse this complex sample composed of peptides from the studied bacteria and its host. Sample was doped before injection in order to calculate p...
ORGANISM(S): Rickettsia slovaca (strain 13-B) 
2018-10-25 | PXD003195 | Pride
Hdmse Xenopus laevis Rickettsia Hi3 
TranscriptomicsMicroarray Expression Data from Haematopoietic Differentiated Human Embryonic Stem Cells
The underlying mechanisms which are responsible and govern early haematopoietic differentiation during development are poorly understood. Gene expression comparison between pluripotent human embryonic stem cells and earliest haematopoietic progenitors may reveal novel transcripts and pathways and p...
ORGANISM(S): Homo sapiens 
2012-01-06 | E-GEOD-29115 | biostudies-arrayexpress
MetabolomicsCyclooxygenase-2, Asymmetric Dimethylarginine, and the Cardiovascular Hazard From Nonsteroidal Anti-Inflammatory Drugs (Murine and human plasma quantitative L-arginine and methylarginines UPLC-MS/MS assay)

BACKGROUND: Large-scale, placebo-controlled trials established that nonsteroidal anti-inflammatory drugs confer a cardiovascular hazard: this has been attributed to depression of cardioprotective products of cyclooxygenase (COX)-2, especially prostacyclin. An alternative mechanis...

2019-08-22 | MTBLS685 | MetaboLights
UnknownResults of the phase IIa RADICAL trial of the FGFR inhibitor AZD4547 in endocrine resistant breast cancer.
Not available
S-EPMC9187670 | biostudies-literature
TranscriptomicsGene Expression Profiles Distinguish Children with Inactive Polyarticular Juvenile Idiopathic Arthritis (JIA) with a Predilection to Flare
Gene expression profiles were obtained from 17 children with rheumatoid factor negative (RF-) polyarticular juvenile idiopathic arthritis (JIA). The disease was inactive in all patients at visit 1. Thee disease remained inactive at visit 2 for 9 patients, while the other 8 patients were experiencing...
ORGANISM(S): Homo sapiens 
2013-12-14 | E-GEOD-26112 | biostudies-arrayexpress
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